SCHEMBL6722904

SCHEMBL6722904

COC(=O)C(C)Oc1ccccc1CCl

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
POLB P06746 1/20 0.47
F9 P00740 1/20 0.42
PLAU P00749 1/20 0.42
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
ALDH1A1 P00352 3/20 0.40
GAA P10253 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MTNR1A P48039 2/20 0.39
MTNR1B P49286 2/20 0.39
TSHR P16473 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480204 0.86 LMNA (0.51) KMT2APOLBHPGDALDH1A1MEN1
SCHEMBL6671933 0.85 ADRB2 (0.41) KMT2APOLBMTNR1AMTNR1B
SCHEMBL4849966 0.85 KMT2A (0.62) KMT2APOLBGAATSHRCYP1A2
SCHEMBL7934338 0.85 KMT2A (0.62) KMT2APOLBGAATSHRCYP1A2
SCHEMBL7846116 0.81 TSHR (0.48) KMT2AHPGDHTTALDH1A1GAA
SCHEMBL14092187 0.81 F9 (0.43) KMT2APOLBF9PLAUHPGD
SCHEMBL7848251 0.81 ALDH1A1 (0.41) KMT2APOLBF9PLAUHPGD
SCHEMBL289668 0.81 ADRA2C (0.49) KMT2AF9PLAUALDH1A1GAA
SCHEMBL28729952 0.79 KMT2A (0.56) KMT2APOLBF9PLAUHPGD
SCHEMBL6671929 0.79 ALOX15 (0.40) KMT2APOLBF9PLAUHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040092402-A1 Pyrimidine derivatives and herbicides containing the same SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2004-05-13 US disclosed
EP-1333029-A1 PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME Sumitomo Chemical Takeda Agro Company, Limited (JP) 2003-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092402-A1 Pyrimidine derivatives and herbicides containing the same DDX41, CBR3, DPYD KMT2A 442/4885POLB 1021/4885F9 4554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.