Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095329 | 0.99 | IGF1R (0.47) | ACMSDIGF1RSIRT1SGMS2MRGPRX4 | |
| SCHEMBL2095326 | 0.82 | PDE4B (0.47) | SGMS2MRGPRX4PDE4APDE4BPDE4C | |
| SCHEMBL5210690 | 0.77 | ACMSD (0.47) | ACMSDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5249481 | 0.76 | HRH3 (0.60) | MRGPRX4KMT2AGAAHRH3SLC6A2 | |
| SCHEMBL22103998 | 0.75 | MEN1 (0.51) | ACMSDMEN1KMT2A | |
| SCHEMBL22103975 | 0.75 | MEN1 (0.51) | ACMSDMEN1KMT2A | |
| SCHEMBL12354455 | 0.75 | SPHK1 (0.60) | IGF1RHRH3SPHK1 | |
| SCHEMBL6700367 | 0.75 | LMNA (0.55) | SIRT1MCL1MEN1ALDH1A1KMT2A | |
| SCHEMBL29134059 | 0.75 | MRGPRX4 (0.40) | SGMS2MRGPRX4PDE4APDE4BPDE4C | |
| SCHEMBL16055979 | 0.75 | CSF1R (0.49) | SGMS2MRGPRX4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259958-A1 | Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2004-12-23 | — | — | US | claimed |
| US-20020128323-A1 | Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2002-09-12 | — | — | US | claimed |
| US-20040259958-A1 | Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2004-12-23 | — | — | US | disclosed |
| US-6790868-B2 | REDUCING THE PRESENCE OF MICROORGANISMS ON A SUBSTRATE OR IN A FLUID ENVIRONMENT | WARNER-LAMBERT COMPANY | 2004-09-14 | — | — | US | disclosed |
| US-20020128323-A1 | Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128323-A1 | Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same | PAOX, NONO, TYR | ACMSD 162/4885IGF1R 4722/4885SIRT1 4630/4885 |
| US-20040259958-A1 | Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same | PAOX, NONO, TYR | ACMSD 162/4885IGF1R 4722/4885SIRT1 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.