Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176066 | 0.87 | CYP2D6 (0.34) | CASRPTPN1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6563216 | 0.85 | KIF11 (0.32) | — | |
| SCHEMBL1269231 | 0.83 | MAPK1 (0.39) | CYP3A4CYP2D6ALDH1A1RAB9AKMT2A | |
| SCHEMBL3709877 | 0.77 | APP (0.33) | CTSK | |
| SCHEMBL10107622 | 0.77 | CTSK (0.31) | HPGDMEN1RAB9AKMT2ACTSK | |
| SCHEMBL10516000 | 0.77 | SQOR (0.35) | CYP3A4KCNH2CYP1A2ALDH1A1HPGD | |
| SCHEMBL10107582 | 0.75 | KCNN4 (0.36) | — | |
| SCHEMBL10400260 | 0.74 | PTPN1 (0.42) | CASRPTPN1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL14339779 | 0.72 | CYP2A6 (0.40) | CASRPTPN1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6724607 | 0.72 | CA1 (0.37) | CYP3A4CYP1A2CYP2A6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677461-B2 | CYANOSILATION CATALYST | JAPAN AS REPRESENTED BY PRESIDENT OF THE UNIVERSITY OF TOKYO (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030119659-A1 | Ligands and asymmetric catalysts made by using the same | JAPAN AS REPRESENTED BY PRESIDENT OF THE UNIVERSITY OF TOKYO (JP) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119659-A1 | Ligands and asymmetric catalysts made by using the same | AP2A1, AP3D1, AP3M1 | CASR 3207/4885PTPN1 341/4885CYP3A4 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.