Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 9/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | CASP1 | P29466 | 5/20 | 0.36 |
| ▸ | CASP7 | P55210 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453996 | 0.78 | CA1 (0.39) | CA1CA2ALDH1A1GAATSHR | |
| SCHEMBL1269231 | 0.76 | MAPK1 (0.39) | ALDH1A1ALOX15KDM4EKMT2AMAPT | |
| SCHEMBL5644819 | 0.74 | ALDH1A1 (0.40) | CA1CA2ALDH1A1ALOX15KDM4E | |
| SCHEMBL6563216 | 0.74 | KIF11 (0.32) | — | |
| SCHEMBL20176069 | 0.74 | CYP1A2 (0.37) | POLBHTTSMN1; SMN2CYP2A6LMNA | |
| SCHEMBL6724604 | 0.72 | CASR (0.37) | CA1CA2ALDH1A1HSD17B10HPGD | |
| SCHEMBL28297056 | 0.71 | ALDH1A1 (0.48) | CA1CA2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6711112 | 0.70 | CA1 (0.41) | CA1CA2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28451515 | 0.68 | TSHR (0.40) | ALDH1A1GAATSHRCYP2A6 | |
| SCHEMBL4770081 | 0.68 | ALDH1A1 (0.44) | CA1CA2ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677461-B2 | CYANOSILATION CATALYST | JAPAN AS REPRESENTED BY PRESIDENT OF THE UNIVERSITY OF TOKYO (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030119659-A1 | Ligands and asymmetric catalysts made by using the same | JAPAN AS REPRESENTED BY PRESIDENT OF THE UNIVERSITY OF TOKYO (JP) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119659-A1 | Ligands and asymmetric catalysts made by using the same | AP2A1, AP3D1, AP3M1 | CA1 2967/4885CA2 2552/4885ALDH1A1 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.