SCHEMBL6724747

SCHEMBL6724747

O=C(Cl)c1cccc(S(=O)(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.52
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.46
LCK P06239 1/20 0.45
FYN P06241 1/20 0.45
LMNA P02545 2/20 0.45
HTT P42858 1/20 0.45
MAPT P10636 1/20 0.44
IL1RN P18510 1/20 0.44
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
GAA P10253 1/20 0.41
F2 P00734 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL726937 0.86 TSHR (0.47) TSHRALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL30525020 0.84 ALDH1A1 (0.46) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL35218 0.84 ALDH1A1 (0.46) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL21726589 0.83 TSHR (0.55) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL3495441 0.83 TSHR (0.61) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL15575570 0.82 ALDH1A1 (0.45) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL6517138 0.82 CA2 (0.46) TSHRALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL10589468 0.82 CA2 (0.59) MAPTCA1CA2
SCHEMBL30901132 0.82 CA2 (0.46) TSHRALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL30901133 0.82 CA2 (0.46) TSHRALDH1A1SMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6676737-B2 INK JET RECORDING; IMAGE QUALITY KONICA CORPORATION (JP) 2004-01-13 US disclosed
US-20010023652-A1 Water based ink composition and image forming method KONICA CORPORATION, A CORP. OF JAPAN (JP) 2001-09-27 US disclosed
EP-1125995-A2 Water based ink composition and image forming method KONICA CORPORATION (JP) 2001-08-22 EP disclosed
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed
US-4046754-A NATURAL FIBERS, POLYAMIDES, REGENERATED CELLULOSE HOECHST AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-4045428-A Water-soluble reactive naphthylazonaphthyl dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed