SCHEMBL726937

SCHEMBL726937

O=C(Cl)c1cccc(S(=O)(=O)c2cccc(C(=O)Cl)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 4/20 0.47
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
HTT P42858 3/20 0.42
F2 P00734 1/20 0.42
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
LOX P28300 3/20 0.41
GAA P10253 2/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
IL1RN P18510 1/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725823 0.93 KMT2A (0.46) TSHRALDH1A1LMNASMN1; SMN2HTT
(Phenylsulfonyl)Benzene SCHEMBL29100684 0.88 HTR6 (0.54) TSHRALDH1A1LMNASMN1; SMN2GAA
SCHEMBL6724747 0.86 TSHR (0.52) TSHRALDH1A1LMNASMN1; SMN2HTT
SCHEMBL35218 0.86 ALDH1A1 (0.46) TSHRALDH1A1LMNASMN1; SMN2HTT
SCHEMBL30525020 0.86 ALDH1A1 (0.46) TSHRALDH1A1LMNASMN1; SMN2HTT
Ammonia Solution, Strong SCHEMBL15575570 0.84 ALDH1A1 (0.45) TSHRALDH1A1LMNASMN1; SMN2HTT
SCHEMBL10589468 0.84 CA2 (0.59) CA1CA2MAPT
SCHEMBL30901133 0.84 CA2 (0.46) TSHRALDH1A1LMNASMN1; SMN2HTT
SCHEMBL6517138 0.84 CA2 (0.46) TSHRALDH1A1LMNASMN1; SMN2HTT
SCHEMBL30901132 0.84 CA2 (0.46) TSHRALDH1A1LMNASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8309655-B2 Methods for the preparation of a poly(arylene ether) polysiloxane multiblock copolymer, multiblock copolymers produced thereby, and associated compositions and articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-11-13 US claimed
EP-2516501-A1 METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER SABIC Innovative Plastics IP B.V. (NL) 2012-10-31 EP claimed
WO-2011077297-A1 METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-06-30 WO claimed
US-20110152471-A1 METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER, MULTIBLOCK COPOLYMERS PRODUCED THEREBY, AND ASSOCIATED COMPOSITIONS AND ARTICLES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-23 US claimed
JP-2010511095-A 2010-04-08 JP claimed
US-20080287598-A1 Method of preparing aramid polymers incorporating carbon nanotubes E. I. DU PONT DE NEMOURS AND COMPANY 2008-11-20 US claimed
WO-2008066838-A1 METHOD OF PREPARING ARAMID POLYMERS INCORPORATING CARBON NANOTUBES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-06-05 WO claimed
WO-2025126940-A1 POLYMER, AROMATIC POLYAMIDE, MOLDED OBJECT, FILM, VIBRATION SENSOR, SPEAKER, AND STRUCTURAL-HEALTH MONITORING SYSTEM 東レ株式会社 2025-06-19 WO disclosed
CN-112625017-A Amide dianhydride, preparation method and application thereof 中国科学院长春应用化学研究所 2021-04-09 CN disclosed
EP-2588656-B1 POLYAMIDE-POLY(ARYLENE ETHER) FIBER AND METHOD FOR ITS PREPARATION SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-01-09 EP disclosed
US-10113055-B2 Article comprising poly(phenylene ether)-polysiloxane copolymer composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-10-30 US disclosed
EP-2516501-B1 METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-11-15 EP disclosed
EP-3140351-A1 ARTICLE COMPRISING POLY (PHENYLENE ETHER)-POLYSILOXANE COPOLYMER COMPOSITION SABIC Global Technologies B.V. (NL) 2017-03-15 EP disclosed
US-4883634-A WATER SWELLING, DRYING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-28 US disclosed
US-4737571-A REACTING PHENYLENEDIAMINE WITH TEREPHTHALOYL CHLORIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-12 US disclosed
US-4684409-A SOLUTION POLYMERIZATION OF AROMATIC POLYAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-04 US disclosed
EP-0229714-A2 Polymerization of aromatic polyamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-22 EP disclosed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 US disclosed
US-3931142-A Heterocyclic containing disazo compounds CIBA-GEIGY AG (CH) 1976-01-06 US disclosed