SCHEMBL6517138

SCHEMBL6517138

O=C(Cl)c1cccc(S(=O)(=O)F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.46
ALDH1A1 P00352 5/20 0.44
TSHR P16473 3/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 5/20 0.40
HTT P42858 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
F2 P00734 2/20 0.40
PRSS1 P07477 2/20 0.40
PRSS2 P07478 2/20 0.40
PRSS3 P35030 2/20 0.40
CA1 P00915 1/20 0.40
MAPT P10636 2/20 0.39
IL1RN P18510 1/20 0.39
KDM4E B2RXH2 1/20 0.39
PTK2B Q14289 1/20 0.39
CYP2C19 P33261 1/20 0.38
AKR1C3 P42330 1/20 0.37
AKR1C1 Q04828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901133 1.00 CA2 (0.46) CA2ALDH1A1TSHRMEN1KMT2A
SCHEMBL30901132 1.00 CA2 (0.46) CA2ALDH1A1TSHRMEN1KMT2A
SCHEMBL726937 0.84 TSHR (0.47) CA2ALDH1A1TSHRKMT2ALMNA
SCHEMBL35218 0.82 ALDH1A1 (0.46) CA2ALDH1A1TSHRMEN1KMT2A
SCHEMBL30901134 0.82 F2 (0.57) CA2ALDH1A1TSHRKMT2ALMNA
SCHEMBL6724747 0.82 TSHR (0.52) CA2ALDH1A1TSHRLMNAHTT
SCHEMBL1436244 0.82 F2 (0.57) CA2ALDH1A1TSHRKMT2ALMNA
SCHEMBL30525020 0.82 ALDH1A1 (0.46) CA2ALDH1A1TSHRMEN1KMT2A
SCHEMBL31196958 0.81 GAA (0.55) CA2ALDH1A1TSHRLMNAF2
Ammonia Solution, Strong SCHEMBL15575570 0.81 ALDH1A1 (0.45) CA2ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376543-A1 HYALURONIC ACID-COLLAGEN COPOLYMER COMPOSITIONS AND MEDICAL APPLICATIONS THEREOF SHANGHAI QISHENG BIOLOGICAL PREPARATION CO LTD (CN) 2025-12-11 US disclosed
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2025-08-19 US disclosed
US-12304974-B2 Hyaluronic acid-collagen copolymer compositions and medical applications thereof SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2025-05-20 US disclosed
US-20240252446-A1 DERIVATIZED COLLAGEN-HYALURONIC ACID BASED IMPLANTS FOR SUSTAINED DELIVERY OF OPHTHALMIC DRUGS SUSTAINED DRUG DELIVERY LLC 2024-08-01 US disclosed
CN-111689929-B Sulfur fluoride (VI) compound and preparation method thereof 斯克里普斯研究所 2024-05-31 CN disclosed
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 EP disclosed
EP-3892610-B1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION SCRIPPS RESEARCH INST (US) 2023-08-16 EP disclosed
WO-2023125689-A1 HYALURONIC ACID-COLLAGEN COPOLYMER COMPOSITIONS AND MEDICAL APPLICATIONS THEREOF SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2023-07-06 WO disclosed
US-20230203207-A1 HYALURONIC ACID-COLLAGEN COPOLYMER COMPOSITIONS AND MEDICAL APPLICATIONS THEREOF SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2023-06-29 US disclosed
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-10-06 US disclosed
US-4883864-A COUPLED AND FREE AMINE GROUPS CAPPED WITH UREA OR AMIDE GROUPS, EYE SURGERY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-28 US disclosed
US-4851513-A Viscoelastic collagen solution for opthalmic use and method of preparation MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-07-25 US disclosed
US-4713446-A COLLAGEN COUPLED TO CARBONYL OR SULFONYL GROUPS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-12-15 US disclosed
EP-0214853-A2 Viscoelastic collagen solution for ophthalmic use and method of preparation MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-18 EP disclosed
US-4273708-A Carbonyl-substituted cyan azo dye-providing materials EASTMAN KODAK COMPANY (US) 1981-06-16 US disclosed
US-4272434-A COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1981-06-09 US disclosed
US-4195993-A AZO DYES EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4183753-A Photographic products and processes employing metal complexed azo dyes EASTMAN KODAK COMPANY (US) 1980-01-15 US disclosed
US-4142891-A WHICH FORM METAL-COMPLEXED DYE TRANSFER IMAGES EASTMAN KODAK COMPANY (US) 1979-03-06 US disclosed
US-4069224-A N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS THE UPJOHN COMPANY (US) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof GRB2, SCTR, OGFR CA2 342/4885ALDH1A1 4622/4885TSHR 7/4885
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF QSOX1, YBX1, SFXN1 CA2 577/4885ALDH1A1 3604/4885TSHR 397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.