SCHEMBL35218

SCHEMBL35218

O=C(Cl)c1cccc(S(=O)(=O)Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 3/20 0.46
LMNA P02545 4/20 0.41
F2 P00734 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HTT P42858 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MAPT P10636 2/20 0.40
IL1RN P18510 1/20 0.40
KDM4E B2RXH2 1/20 0.40
PTK2B Q14289 1/20 0.40
CYP2C19 P33261 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525020 1.00 ALDH1A1 (0.46) ALDH1A1HSD17B10TDP1TSHRLMNA
Ammonia Solution, Strong SCHEMBL15575570 0.98 ALDH1A1 (0.45) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL726937 0.86 TSHR (0.47) ALDH1A1TSHRLMNAF2PRSS1
SCHEMBL6888383 0.86 LMNA (0.54) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL8673267 0.84 AKR1C3 (0.45) ALDH1A1LMNASMN1; SMN2MAPTAKR1C3
SCHEMBL35030 0.84 F2 (0.57) ALDH1A1HSD17B10TDP1TSHRF2
SCHEMBL6724747 0.84 TSHR (0.52) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL29792725 0.84 F2 (0.57) ALDH1A1HSD17B10TDP1TSHRF2
SCHEMBL10589468 0.82 CA2 (0.59) CA1CA2MAPT
SCHEMBL533063 0.82 ALDH1A1 (0.55) ALDH1A1HSD17B10TDP1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978411-A Soxhlet dendritic macromolecular compound and preparation method and application thereof 华东师范大学 2025-05-13 CN claimed
CN-118666759-A Novel benzenesulfonamide compound and preparation method and application thereof 智元柏迈(杭州)科技有限公司 2024-09-20 CN claimed
CN-117858385-B Multilayer PCB and preparation method thereof 深圳市点成电路板有限公司 2024-06-18 CN claimed
CN-117858385-A Multilayer PCB and preparation method thereof 深圳市点成电路板有限公司 2024-04-09 CN claimed
CN-117126138-A Compound for degrading target protein in ubiquitin-proteasome system, and preparation method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2023-11-28 CN claimed
CN-112062951-B One-pot catalytic synthesis method for interfacial polymerization of fatty polyamide sulfonamide 庆阳职业技术学院 2023-04-14 CN claimed
CN-112062952-B Aromatic polyamide sulfamide solution polycondensation one-pot catalytic synthesis method 庆阳职业技术学院 2023-04-14 CN claimed
US-10189804-B2 Method for producing dicarboxylic acid compound DAIICHI SANKYO COMPANY, LIMITED (JP) 2019-01-29 US claimed
CN-108395389-A The method for preparing 3- chlorine sulfonyl-benzoyl chlorine 江苏佳麦化工有限公司 2018-08-14 CN claimed
US-20180148424-A1 METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-05-31 US claimed
EP-3287448-A1 METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-02-28 EP claimed
CN-103342812-A Aromatic polyamide sulfamide and preparation method thereof UNIV DALIAN POLYTECHNIC 2013-10-09 CN claimed
CN-102093320-B Soluble epoxide hydrolase inhibitor SHANGHAI HAINI PHARMACEUTICAL CO LTD YANGTZE RIVER PHARMACEUTICAL GROUP 2013-08-28 CN claimed
CN-102093320-A Soluble epoxide hydrolase inhibitor SHANGHAI HAINI PHARMACEUTICAL CO LTD YANGTZE RIVER PHARMACEUTICAL GROUP 2011-06-15 CN claimed
CN-100558704-C The dichloro monomer and the synthetic method thereof of the sulfone ketone containing structure of poly (aryl ether sulfone ketone) DALIAN LIGHT IND COLLEGE (CN) 2009-11-11 CN claimed
CN-1974549-A Dichloro monomer containing sulfuryl ketone structure for polyaryl ether sulfuryl ketone and its synthesis process DALIAN LIGHT IND COLLEGE (CN) 2007-06-06 CN claimed
EP-0154811-A2 Coupling agents between mineral fillers and polymers Plüss-Staufer AG (CH) 1985-09-18 EP claimed
WO-1985003505-A2 COUPLING AGENT BETWEEN MINERAL FILLERS AND POLYMERS PLÜSS-STAUFER AG (CH) 1985-08-15 WO claimed
US-4212819-A Process for the preparation of benzoyl halide and halosulfonylbenzoyl halide HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-07-15 US claimed
US-4110373-A Process for the preparation of benzoyl halide and halosulfonylbenzoyl halide HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-08-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189804-B2 Method for producing dicarboxylic acid compound PC, CPS1, PCCA ALDH1A1 294/4885HSD17B10 146/4885TDP1 3245/4885
US-20180148424-A1 METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND PC, CPS1, PCCA ALDH1A1 294/4885HSD17B10 146/4885TDP1 3245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.