SCHEMBL672518

SCHEMBL672518

CC(c1ccc(I)cc1)c1ccc(I)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.52
PDCD1 Q15116 1/20 0.52
ESR2 Q92731 1/20 0.52
CD274 Q9NZQ7 1/20 0.52
ACACB O00763 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
APEX1 P27695 1/20 0.37
PMP22 Q01453 1/20 0.37
HDAC8 Q9BY41 2/20 0.35
ALOX5AP P20292 1/20 0.34
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
GSK3B P49841 1/20 0.32
TPMT P51580 1/20 0.32
APP P05067 1/20 0.31
ADRB2 P07550 1/20 0.31
PSMB1 P20618 1/20 0.31
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14160147 0.89 ESR1 (0.44) ESR1PDCD1ESR2CD274CYP2D6
SCHEMBL14160194 0.89 ESR1 (0.44) ESR1PDCD1ESR2CD274ACACB
SCHEMBL9440183 0.87 ESR1 (0.42) ESR1PDCD1ESR2CD274ACACB
SCHEMBL10714 0.81 TYR (0.46) ACACBCYP1A2CYP2D6
SCHEMBL4867593 0.77 NOS3 (0.45) ESR1PDCD1ESR2CD274ACACB
SCHEMBL2391380 0.77 ADRB2 (0.56) ACACBCYP1A2CYP2D6APEX1PMP22
SCHEMBL18243011 0.77 ACACB (0.41) ESR1PDCD1ESR2CD274ACACB
SCHEMBL1140338 0.77 ADRB2 (0.56) ACACBCYP1A2CYP2D6APEX1PMP22
SCHEMBL6556654 0.77 ACACB (0.37) ESR1PDCD1ESR2CD274ACACB
SCHEMBL1625341 0.77 NOS3 (0.45) ESR1PDCD1ESR2CD274ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 908 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER SHPP GLOBAL TECH B V (NL) 2026-05-14 US disclosed
EP-4720194-A1 POLYCARBONATE COPOLYMER COMPOSITIONS SHPP Global Technologies B.V. (NL) 2026-04-08 EP disclosed
EP-4716968-A1 BATTERY PACK COVER WITH A PROTRUDING DOUBLE WALL BATTERY DIVIDER AND THERMAL RUNAWAY BARRIER SABIC Global Technologies B.V. (NL) 2026-04-01 EP disclosed
EP-4605473-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECH BV (NL) 2026-04-01 EP disclosed
EP-4684445-A1 BATTERY PACK WITH BATTERY MODULE PARTIALLY SUBMERGED IN COOLANT SABIC Global Technologies B.V. (NL) 2026-01-28 EP disclosed
US-20260002025-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFORE, AND METHODS FOR THE MANUFACTURE THEREOF SHPP GLOBAL TECH BV (NL) 2026-01-01 US disclosed
US-12503593-B2 Curable thermosetting composition including poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-12-23 US disclosed
EP-4663691-A1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE COMPOSITION SHPP Global Technologies B.V. (NL) 2025-12-17 EP disclosed
US-20250364623-A1 BATTERY PACK WITH THERMOPLASTIC BARRIER BETWEEN CELLS SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-11-27 US disclosed
US-4086212-A ESTERIFICATION OR TRANSESTERIFICATION BAYER AKTIENGESELLSCHAFT (DT) 1978-04-25 US disclosed
US-4024093-A Flame retardant polyphenylene ether resin compositions containing a halogenated flame retardant and selected organic iron salts GENERAL ELECTRIC COMPANY (US) 1977-05-17 US disclosed
US-4020124-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and graft polymerized high rubber content polymers GENERAL ELECTRIC COMPANY (US) 1977-04-26 US disclosed
US-4013613-A INCLUDING ADDITION POLYMER GENERAL ELECTRIC COMPANY (US) 1977-03-22 US disclosed
US-4002581-A MOLDINGS GENERAL ELECTRIC COMPANY (US) 1977-01-11 US disclosed
US-3981841-A MOLDING MATERIALS, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1976-09-21 US disclosed
US-3974235-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and flame retardant GENERAL ELECTRIC COMPANY (US) 1976-08-10 US disclosed
US-3959211-A ETHYLENE-ALPHA-OLEFIN-DIENE GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed
US-3953394-A POLYETHYLENE TEREPHTHALATE-POLYBUTYLENE TEREPHTHALATE BLENDS GENERAL ELECTRIC COMPANY (US) 1976-04-27 US disclosed
US-3943191-A MOLDING GENERAL ELECTRIC COMPANY (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION CYP46A1, RPTOR, PCNA ESR1 275/4885PDCD1 4623/4885ESR2 344/4885
US-20260002025-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFORE, AND METHODS FOR THE MANUFACTURE THEREOF LCP1, COL2A1, SHBG ESR1 11/4885PDCD1 4174/4885ESR2 38/4885
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER CBLB, UBE4A, PSMD14 ESR1 681/4885PDCD1 1131/4885ESR2 1490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.