Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 7/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723591 | 0.85 | THRA (0.46) | LMNAALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL6721180 | 0.85 | ALDH1A1 (0.43) | LMNAALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL6725936 | 0.83 | GAA (0.40) | LMNAALDH1A1KDM4EPOLBNPSR1 | |
| SCHEMBL6723918 | 0.80 | ALDH1A1 (0.47) | LMNAALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL6731605 | 0.78 | ALDH1A1 (0.45) | LMNAALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL22991665 | 0.77 | CDC25B (0.46) | LMNAALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL6721262 | 0.75 | IDO1 (0.42) | LMNAL3MBTL1HPGD | |
| SCHEMBL5908191 | 0.74 | GAA (0.59) | LMNAALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL24588544 | 0.70 | CA12 (0.43) | ALDH1A1KDM4ECDC25BMEN1MAPT | |
| SCHEMBL6723683 | 0.70 | TPMT (0.47) | LMNAALDH1A1MAPK1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |