Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413782 | 0.82 | PPARD (0.47) | PPARGPPARDPPARA | |
| SCHEMBL3419255 | 0.81 | TRPV1 (0.48) | PPARGTRPV1PPARDPPARAPTGS2 | |
| SCHEMBL3413160 | 0.80 | PPARG (0.44) | PPARGPPARDPPARA | |
| SCHEMBL3415962 | 0.79 | PPARD (0.58) | PPARGPPARDPPARA | |
| SCHEMBL6726299 | 0.78 | PTGS2 (0.42) | PTGS2 | |
| SCHEMBL3418866 | 0.78 | PPARD (0.54) | PPARGPPARDPPARA | |
| SCHEMBL3418523 | 0.77 | PPARD (0.53) | PPARGPPARDPPARA | |
| SCHEMBL3416129 | 0.77 | PPARD (0.49) | PPARGPPARDPPARA | |
| SCHEMBL3419423 | 0.76 | PPARD (0.49) | PPARGPPARDPPARA | |
| SCHEMBL3414069 | 0.76 | PPARG (0.40) | PPARGPPARDPPARAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | GPR119, NR3C1, INSR | PPARG 238/4885TRPV1 3091/4885PPARD 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.