Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.42 |
| ▸ | FAAH | O00519 | 6/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413165 | 0.81 | SYK (0.37) | — | |
| SCHEMBL6726294 | 0.78 | PPARG (0.46) | PTGS2 | |
| SCHEMBL4396277 | 0.70 | PTGS1 (0.48) | PTGS2FAAH | |
| SCHEMBL29800023 | 0.70 | PTGS1 (0.48) | PTGS2FAAH | |
| SCHEMBL3418744 | 0.69 | MTNR1A (0.39) | — | |
| SCHEMBL3667215 | 0.67 | AKR1C3 (0.52) | PTGS2AKR1C3AKR1C2 | |
| SCHEMBL3673447 | 0.66 | PTGS1 (0.63) | PTGS2AKR1C3AKR1C2 | |
| SCHEMBL24031605 | 0.64 | MAPK1 (0.47) | — | |
| SCHEMBL8882999 | 0.64 | ATR (0.45) | — | |
| SCHEMBL566467 | 0.64 | CREBBP (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | GPR119, NR3C1, INSR | PTGS2 3150/4885FAAH 2613/4885AKR1C3 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.