Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329791 | 0.90 | LMNA (0.44) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL4341658 | 0.88 | MAPT (0.48) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4327192 | 0.87 | CYP1A2 (0.56) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL4335538 | 0.87 | KMT2A (0.45) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL4335160 | 0.86 | LMNA (0.48) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4332195 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL4341925 | 0.84 | ALDH1A1 (0.40) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4328015 | 0.84 | NPC1 (0.47) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL4334182 | 0.84 | MGLL (0.45) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4335130 | 0.82 | FPR2 (0.47) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | GPR119, IRS1, SLC5A1 | MAPT 4654/4885ALDH1A1 844/4885KMT2A 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.