Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736658 | 0.71 | HTT (0.35) | MEN1ALDH1A1KMT2AEGFRKDR | |
| SCHEMBL6658600 | 0.69 | GABRA1 (0.33) | EGFRKDR | |
| SCHEMBL7913558 | 0.67 | ADRA2A (0.59) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6734341 | 0.65 | HTT (0.40) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7913597 | 0.60 | MAOA (0.55) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28231042 | 0.60 | ADRA2A (0.47) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL23120078 | 0.57 | MAOA (0.55) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2564016 | 0.57 | MAOA (0.55) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15360072 | 0.57 | — | — | |
| SCHEMBL26756454 | 0.57 | ALDH1A1 (0.37) | KDM4EALDH1A1EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063580-A1 | Bicyclic triazolone derivatives and a herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1333031-A1 | BICYCLIC TRIAZOLONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063580-A1 | Bicyclic triazolone derivatives and a herbicides containing the same | WEE1, WEE2, BAK1 | KDM4E 1331/4885MEN1 4301/4885ALDH1A1 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.