SCHEMBL6730199

SCHEMBL6730199

Cc1cccc(Cl)c1S(N)(=O)=S

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.41
NR3C1 P04150 1/20 0.39
GAA P10253 1/20 0.38
ALDH1A1 P00352 3/20 0.36
CCR1 P32246 2/20 0.35
ATM Q13315 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
GRIA1 P42261 1/20 0.34
CACNG8 Q8WXS5 1/20 0.34
LMNA P02545 1/20 0.34
AKR1C3 P42330 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ESR1 P03372 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6729028 0.86 CA1 (0.38) ALDH1A1ATMKMT2ATDP1
SCHEMBL4440346 0.84 SLC40A1 (0.43) SLC40A1NR3C1ALDH1A1CCR1ATM
SCHEMBL13131553 0.78 SLC40A1 (0.44) SLC40A1NR3C1ALDH1A1CCR1ATM
SCHEMBL154899 0.78 SLC40A1 (0.44) SLC40A1NR3C1ALDH1A1CCR1ATM
SCHEMBL29907223 0.78 SLC40A1 (0.44) SLC40A1NR3C1ALDH1A1CCR1ATM
SCHEMBL6734279 0.77 ACHE (0.41) ALDH1A1KMT2APTGES2
SCHEMBL4618467 0.76 SLC40A1 (0.43) SLC40A1NR3C1ALDH1A1CCR1ATM
SCHEMBL4635992 0.76 SLC40A1 (0.43) SLC40A1NR3C1GAAALDH1A1CCR1
SCHEMBL11950241 0.76 SLC40A1 (0.50) SLC40A1NR3C1GAAALDH1A1CCR1
Hydrochloric Acid SCHEMBL4303872 0.74 SLC40A1 (0.42) SLC40A1NR3C1GAAALDH1A1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6677277-B1 Substituted sulphonyl amino(thio)carbonyl compounds and their use as herbicides BAYER AKTIENGESELLSCHAFT (DE) 2004-01-13 US disclosed