Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734279 | 0.86 | ACHE (0.41) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL6730199 | 0.86 | SLC40A1 (0.41) | ATMALDH1A1KMT2ATDP1 | |
| SCHEMBL9819451 | 0.81 | CA2 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1954846 | 0.80 | CA1 (0.45) | CA1CA2CA9CA12CA7 | |
| SCHEMBL8338643 | 0.74 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2052455 | 0.74 | KMT2A (0.45) | CA1CA2CA9CA7KEAP1 | |
| SCHEMBL29469942 | 0.73 | TRPA1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL3296375 | 0.73 | TRPA1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1523492 | 0.73 | CD44 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1925949 | 0.73 | CA2 (0.45) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677277-B1 | Substituted sulphonyl amino(thio)carbonyl compounds and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |