Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674663 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL8859065 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL673965 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2A | |
| SCHEMBL17955311 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL12411256 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL8553854 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL8553851 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL12411252 | 0.74 | NPC1 (0.49) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL11206642 | 0.74 | NPC1 (0.49) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL8088256 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873168-B1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORP (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-7968652-B2 | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |