SCHEMBL674663

SCHEMBL674663

CCN(CC)C(=CCCCN)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
SLC6A4 P31645 5/20 0.38
ESR1 P03372 1/20 0.38
CYP19A1 P11511 1/20 0.38
ESR2 Q92731 1/20 0.38
ADRA2C P18825 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
MAPT P10636 1/20 0.37
MAOA P21397 1/20 0.36
SLC6A2 P23975 5/20 0.36
NPC1 O15118 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC6A3 Q01959 4/20 0.35
CYP2D6 P10635 1/20 0.35
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8773365 0.83 SIGMAR1 (0.42) ALDH1A1ADRA2CSIGMAR1MAPTMAOA
SCHEMBL673022 0.82 ALDH1A1 (0.44) ALDH1A1HPGDSLC6A4MAPTSLC6A2
SCHEMBL8859065 0.74 ALDH1A1 (0.47) ALDH1A1HPGDSLC6A4MAPTSLC6A2
SCHEMBL12411256 0.74 ALDH1A1 (0.50) ALDH1A1HPGDMAPTNPC1L3MBTL1
SCHEMBL17955311 0.74 ALDH1A1 (0.50) ALDH1A1HPGDMAPTNPC1L3MBTL1
SCHEMBL9403559 0.72 MAPT (0.41) ALDH1A1ESR1CYP19A1ESR2MAPT
SCHEMBL8088261 0.72 ALDH1A1 (0.44) ALDH1A1HPGDSLC6A4MAPTSLC6A2
SCHEMBL8088256 0.72 ALDH1A1 (0.44) ALDH1A1HPGDSLC6A4MAPTSLC6A2
SCHEMBL8553851 0.71 ALDH1A1 (0.41) ALDH1A1HPGDMAPTNPC1L3MBTL1
SCHEMBL8553854 0.71 ALDH1A1 (0.41) ALDH1A1HPGDMAPTNPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP claimed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US claimed
US-7671136-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-03-02 US claimed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US claimed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP claimed
US-20060025539-A1 Modified polymers prepared with lanthanide-based catalysts OZAWA YOICHI 2006-02-02 US claimed
US-6977281-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2005-12-20 US claimed
EP-1237935-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS Bridgestone Corporation (JP) 2002-09-11 EP claimed
WO-2001034659-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO claimed
CN-111051361-B Rubber composition 株式会社LG化学 2023-06-20 CN disclosed
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP disclosed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US disclosed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US disclosed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP disclosed