Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553854 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL673022 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL17955311 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL12411256 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL7084378 | 0.74 | NFE2L2 (0.39) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL8859065 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL674663 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL11320823 | 0.71 | CYP19A1 (0.36) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL11320822 | 0.71 | CYP19A1 (0.36) | ALDH1A1HPGDMAPTNPC1L3MBTL1 | |
| SCHEMBL11206642 | 0.71 | NPC1 (0.49) | ALDH1A1HPGDMAPTNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503958-B1 | Heterocyclic compounds and their production | NIPPON PAINT CO LTD (JP) | 1998-09-23 | — | — | EP | disclosed |
| US-5496943-A | USING UNSATURATED ACYLISOCYANATE COMPOUNDS TO FORM OXAZOLINES, PYRANS WITH AMINOCARBONYLHETERO SUBSTITUTION AND GLUTARIMIDE DERIVATIVES AS CHEMICAL INTERMEDIATES | NIPPON PAINT CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0503958-A2 | Heterocyclic compounds and their production | Nippon Paint Co., Ltd. (JP) | 1992-09-16 | — | — | EP | disclosed |