Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 6/20 | 0.49 |
| ▸ | THRA | P10827 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HRH2 | P25021 | 5/20 | 0.49 |
| ▸ | HRH1 | P35367 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598618 | 1.00 | DGKA (0.50) | DGKATHRBTHRAALDH1A1HRH2 | |
| SCHEMBL13601497 | 0.95 | THRB (0.56) | DGKATHRBTHRAALDH1A1HRH2 | |
| SCHEMBL4979398 | 0.93 | NAAA (0.56) | DGKATHRBTHRALMNAMAPT | |
| SCHEMBL12014425 | 0.93 | ALDH1A1 (0.57) | DGKATHRBTHRAALDH1A1HRH2 | |
| SCHEMBL11711713 | 0.93 | NAAA (0.56) | DGKATHRBTHRALMNAMAPT | |
| SCHEMBL12014422 | 0.91 | ALDH1A1 (0.59) | DGKATHRBTHRAALDH1A1HRH2 | |
| SCHEMBL31259111 | 0.91 | ALDH1A1 (0.59) | DGKATHRBTHRAALDH1A1HRH2 | |
| SCHEMBL419258 | 0.89 | ALDH1A1 (0.46) | DGKATHRBTHRAALDH1A1HRH2 | |
| SCHEMBL674334 | 0.89 | ALDH1A1 (0.46) | DGKATHRBTHRAALDH1A1HRH2 | |
| SCHEMBL65326 | 0.89 | THRB (0.60) | THRBTHRAALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456746-B1 | TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE | BRIDGESTONE CORP (JP) | 2023-04-19 | — | — | EP | disclosed |
| US-11292771-B2 | Amidine catalyst for curable compositions | SIKA TECHNOLOGY AG (CH) | 2022-04-05 | — | — | US | disclosed |
| CN-107771175-B | Amidine catalysts for curable compositions | SIKA技术股份公司 | 2022-01-28 | — | — | CN | disclosed |
| EP-3851489-A1 | MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT | BRIDGESTONE CORPORATION (JP) | 2021-07-21 | — | — | EP | disclosed |
| EP-3757094-A1 | AMIDINE CATALYST FOR CURABLE COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2020-12-30 | — | — | EP | disclosed |
| US-10875937-B2 | Terminal-modified conjugated diene polymer, rubber composition and rubber article | BRIDGESTONE CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| CN-109071685-B | Terminal-modified conjugated diene polymer, rubber composition, and rubber article | 株式会社普利司通 | 2020-12-01 | — | — | CN | disclosed |
| CN-107428941-B | Amidino group-containing catalyst | SIKA技术股份公司 | 2020-11-24 | — | — | CN | disclosed |
| US-20110196086-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-08-11 | — | — | US | disclosed |
| US-7968652-B2 | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| EP-2336233-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-20100160530-A1 | RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE | BRIDGESTRONE CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-1975200-A1 | RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE | Bridgestone Corporation (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-20080177017-A1 | Modified Polymer, Rubber Composition, and Tire | BRIDGESTONE CORPORATION (JP) | 2008-07-24 | — | — | US | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |
| EP-1834966-A1 | MODIFIED POLYMER, RUBBER COMPOSITION, AND TIRE | Bridgestone Corporation (JP) | 2007-09-19 | — | — | EP | disclosed |
| US-7199185-B2 | Use of reactive polymeric surfactants in the formation of emulsions | SYNGENTA LIMITED (GB) | 2007-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292771-B2 | Amidine catalyst for curable compositions | ADM2, GMNN, ARG1 | DGKA 3950/4885THRB 4821/4885THRA 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.