SCHEMBL6733331

SCHEMBL6733331

O=C(O)COc1cccc(S(=O)(=O)OP(c2ccccc2)(c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.50
LMNA P02545 1/20 0.49
CA12 O43570 4/20 0.48
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA4 P22748 4/20 0.48
CA9 Q16790 4/20 0.48
PTPN7 P35236 1/20 0.47
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 1/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PLA2G10 O15496 1/20 0.43
PLA2G2A P14555 1/20 0.43
TBXA2R P21731 1/20 0.42
TBXAS1 P24557 1/20 0.42
PSEN1 P49768 2/20 0.42
PSEN2 P49810 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6552442 0.89 ALOX15 (0.49) ALOX15LMNACA12CA1CA2
SCHEMBL6729616 0.79 PPARA (0.51) ALOX15LMNACA12CA1CA2
SCHEMBL9354238 0.78 LMNA (0.58) ALOX15LMNACA12CA1CA2
SCHEMBL8544679 0.77 LMNA (0.58) ALOX15LMNACA12CA1CA2
SCHEMBL3906802 0.77 AKR1C3 (0.51) LMNACA1CA2ALDH1A1TSHR
SCHEMBL20915130 0.77 CA2 (0.60) ALOX15LMNACA12CA1CA2
SCHEMBL413254 0.74 LMNA (0.81) ALOX15LMNAPTPN7MAPK1ALDH1A1
SCHEMBL3910534 0.73 ALDH1A1 (0.48) LMNACA12CA1CA2CA9
SCHEMBL7327957 0.72 MEN1 (0.58) ALOX15LMNACA12CA1CA2
Tetraphenylphosphonium SCHEMBL6733327 0.72 ALOX15 (0.49) ALOX15LMNACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6761968-B2 FOR A HEAT-SENSITIVE TRANSFER RIBBON; INERT INORGANIC PARTICLES TEIJIN LIMITED (JP) 2004-07-13 US disclosed
US-20040028925-A1 Heat sensitive element transferring films TEIJIN LIMITED (JP) 2004-02-12 US disclosed
EP-1350613-A1 BIAXIALLY ORIENTED POLYESTER FILM TEIJIN LIMITED (JP) 2003-10-08 EP disclosed