Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA4 | P22748 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332517 | 0.84 | F2 (0.54) | LMNAALOX15F2PTPN7ALDH1A1 | |
| SCHEMBL7327550 | 0.84 | TDP1 (0.53) | LMNAALOX15F2PTPN7ALDH1A1 | |
| SCHEMBL7333897 | 0.82 | F2 (0.59) | LMNAALOX15F2PTPN7CA12 | |
| SCHEMBL413254 | 0.82 | LMNA (0.81) | LMNAALOX15PTPN7ALDH1A1MAPK1 | |
| SCHEMBL9354238 | 0.80 | LMNA (0.58) | LMNAALOX15PTPN7CA12CA1 | |
| SCHEMBL7334463 | 0.79 | LMNA (0.67) | LMNAALOX15SMN1; SMN2MAPK1 | |
| SCHEMBL7324955 | 0.78 | FAAH (0.50) | LMNACA12CA1CA2CA4 | |
| SCHEMBL20915130 | 0.78 | CA2 (0.60) | LMNAALOX15PTPN7CA12CA1 | |
| SCHEMBL6733331 | 0.77 | ALOX15 (0.50) | LMNAALOX15PTPN7CA12CA1 | |
| SCHEMBL8782313 | 0.77 | LMNA (0.69) | LMNAALOX15PTPN7ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |