Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741934 | 0.78 | KDM1A (0.38) | SLC1A2KCNH2KDM1ACNR1NAMPT | |
| SCHEMBL6741203 | 0.78 | KCNJ1 (0.47) | KCNH2KDM1ACHRNA7ALDH1A1 | |
| SCHEMBL6739625 | 0.78 | POLB (0.48) | POLBMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6743201 | 0.77 | NAMPT (0.44) | KCNH2KDM1ANAMPTCHRNA7CHRM4 | |
| SCHEMBL6741315 | 0.77 | KCNJ1 (0.46) | KCNH2KDM1ACHRNA7ALDH1A1 | |
| SCHEMBL6736841 | 0.74 | HTR1A (0.41) | KCNH2KDM1ANAMPTCHRNA7 | |
| SCHEMBL6742864 | 0.72 | KCNH2 (0.44) | KCNH2POLBMAPTMEN1KMT2A | |
| SCHEMBL6741876 | 0.72 | NAMPT (0.39) | KCNH2KDM1ANAMPTPOLBMAPT | |
| SCHEMBL7948923 | 0.71 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL21169574 | 0.70 | CNR1 (0.53) | SLC1A2KCNH2CNR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229900-A1 | Bispidine compounds useful in the treatment of cardiac arrythmias | ASTRAZENECA AB (SE) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229900-A1 | Bispidine compounds useful in the treatment of cardiac arrythmias | ADRA1B, ADRB2, ADRA1D | SLC1A2 1938/4885KCNH2 13/4885KDM1A 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.