SCHEMBL6733796

SCHEMBL6733796

O=S(=O)(c1ccc(O)cc1)C1(S(=O)(=O)c2ccc(O)cc2)C=CCC=C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
CA2 P00918 5/20 0.42
CA1 P00915 3/20 0.42
CA12 O43570 2/20 0.42
CA9 Q16790 2/20 0.42
ENPP2 Q13822 1/20 0.42
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
CA7 P43166 1/20 0.35
MMP2 P08253 2/20 0.35
MMP14 P50281 2/20 0.35
MMP1 P03956 1/20 0.35
MMP13 P45452 1/20 0.35
ESR1 P03372 4/20 0.34
KMT2A Q03164 2/20 0.34
RAPGEF4 Q8WZA2 1/20 0.33
EEF2K O00418 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
MMP3 P08254 1/20 0.31
MMP7 P09237 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2221630 0.74 GAA (0.57) LMNACA2CA1CA12CA9
SCHEMBL6733797 0.69 LMNA (0.39) LMNACA2CA1CA12CA9
SCHEMBL16319030 0.68 LMNA (0.38) LMNACA2CA1CA12CA9
SCHEMBL18838 0.64 GAA (0.67) LMNACA2CA1CA12CA9
SCHEMBL29724901 0.64 GAA (0.67) LMNACA2CA1CA12CA9
SCHEMBL124022 0.64 GAA (0.67) LMNACA2CA1CA12CA9
SCHEMBL8028971 0.64 LMNA (0.65) LMNACA2CA1CA12CA9
SCHEMBL547730 0.64 LMNA (0.65) LMNACA2CA1CA12CA9
SCHEMBL3792342 0.64 GAA (0.67) LMNACA2CA1CA12CA9
SCHEMBL8369054 0.63 CA2 (0.57) LMNACA2CA1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4130152-A1 GLASS-FIBER-CONTAINING FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION AND MOLDED OBJECT ADEKA CORPORATION (JP) 2023-02-08 EP disclosed
US-20040249022-A1 Method for the preparation of flameproof hermoplastic resin compositions CHI MEI CORPORATION (TW) 2004-12-09 US disclosed
US-20030162870-A1 Flame-retardant resin composition ASAHI DENKA CO., LTD. (JP) 2003-08-28 US disclosed
EP-1304350-A1 Flame-retardant resin composition Asahi Denka Co., Ltd. (JP) 2003-04-23 EP disclosed