SCHEMBL6733950

SCHEMBL6733950

CC(C)(C)OC(=O)N1CCCN(S(=O)(=O)c2cc3cc(Cl)ccc3n2S(=O)(=O)c2ccccc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.47
PPARA Q07869 3/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ACLY P53396 2/20 0.44
PPARD Q03181 2/20 0.44
STS P08842 2/20 0.43
TGM2 P21980 9/20 0.42
F13A1 P00488 6/20 0.42
TGM1 P22735 3/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.42
TGM3 Q08188 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6730443 0.96 PPARG (0.50) PPARGPPARAPPARDSTSTGM2
SCHEMBL6737259 0.86 TGM2 (0.48) TGM2F13A1TGM1TGM3
SCHEMBL6838890 0.85 STS (0.51) MEN1KMT2ASTSTGM2F13A1
SCHEMBL6737197 0.81 MAPT (0.48) MEN1KMT2ASTSTGM2F13A1
SCHEMBL6728796 0.80 PPARG (0.45) PPARGPPARAPPARDPTGDR2
SCHEMBL6732091 0.80 PPARG (0.45) PPARGPPARAPPARDPTGDR2
SCHEMBL6730405 0.79 MAPT (0.51) MEN1KMT2ASTSTGM2F13A1
SCHEMBL6728310 0.78 PPARG (0.44) PPARGPPARAPPARDPTGDR2
SCHEMBL6787295 0.78 OPRK1 (0.44) PPARGPPARAPPARDPTGDR2
SCHEMBL6736332 0.78 ACLY (0.49) PPARGPPARAMEN1KMT2AACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 PPARG 1204/4885PPARA 573/4885MEN1 2216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.