SCHEMBL6737259

SCHEMBL6737259

CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 11/20 0.48
F13A1 P00488 8/20 0.48
TGM1 P22735 5/20 0.48
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
HTR6 P50406 1/20 0.45
PIK3CA P42336 1/20 0.44
CNR2 P34972 1/20 0.43
NR1H2 P55055 1/20 0.43
GPR119 Q8TDV5 2/20 0.43
TGFBR1 P36897 1/20 0.43
TGM3 Q08188 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838890 0.90 STS (0.51) TGM2F13A1TGM1CHRM2CHRM4
SCHEMBL6730443 0.89 PPARG (0.50) TGM2F13A1TGM1TGM3
SCHEMBL6733950 0.86 PPARG (0.47) TGM2F13A1TGM1TGM3
SCHEMBL2252120 0.83 TGM2 (0.63) TGM2F13A1TGM1GPR119
SCHEMBL23923494 0.81 TGM2 (0.48) TGM2F13A1TGM1TGFBR1TGM3
SCHEMBL6790392 0.77 PKM (0.65) TGM2F13A1TGM1
SCHEMBL6375022 0.75 STS (0.52) HTR6PIK3CANR1H2GPR119TGFBR1
SCHEMBL5203030 0.74 TGFBR1 (0.46) HTR6PIK3CANR1H2GPR119TGFBR1
SCHEMBL3644720 0.73 MAPT (0.62) TGM2F13A1TGM1
SCHEMBL13765376 0.73 SMN1; SMN2 (0.46) TGM2F13A1TGM1CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 TGM2 1707/4885F13A1 15/4885TGM1 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.