SCHEMBL7713669

SCHEMBL7713669

Nc1cccc(Oc2cccc(N)c2C(=O)O)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
MMP2 P08253 1/20 0.44
HTT P42858 1/20 0.39
CTNNB1 P35222 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28415540 0.87 NCOA1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL6741095 0.85 GAA (0.46) CA12CA1CA2CA7CA9
SCHEMBL284305 0.84 CA12 (0.74) CA12CA1CA2CA7CA9
SCHEMBL6734541 0.83 ALDH1A1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL1000014 0.82 MMP2 (0.54) CA12CA1CA2CA7CA9
SCHEMBL6469761 0.80 ALDH1A1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL15971390 0.80 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL7781072 0.80 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL18043789 0.78 MMP2 (0.50) CA12CA1CA2CA7CA9
SCHEMBL9873829 0.77 CYP1A2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372859-B1 MAKING A PASTE BY MIXING A SOLUTION OF HEAT-RESISTANT RESIN A IN A SOLVENT, FINE PARTICLES OF RESIN B INSOLUBLE IN THE SOLVENT BUT SOLUBLE UPON HEATING; HEATING TO DISSOLVE; COOLING TO DEPOSIT OR DISPERSE THE PARTICLES; CURING HITACHI CHEMICAL COMPANY, LTD. (JP) 2002-04-16 US disclosed
EP-0984051-A1 HEAT-RESISTANT ADHESIVES AND SEMICONDUCTOR DEVICES PRODUCED THEREWITH HITACHI CHEMICAL COMPANY, LTD. (JP) 2000-03-08 EP disclosed