Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684789 | 0.86 | TSHR (0.43) | TSHRCA2CA1LMNAUSP2 | |
| SCHEMBL6738638 | 0.85 | MAPT (0.38) | TSHRCA2CA1USP2 | |
| SCHEMBL6740256 | 0.80 | TSHR (0.39) | TSHRCA2CA1LMNAUSP2 | |
| SCHEMBL6740254 | 0.80 | TSHR (0.39) | TSHRCA2CA1LMNAUSP2 | |
| SCHEMBL7217371 | 0.78 | CA2 (0.48) | TSHRCA2CA1LMNAALOX15 | |
| SCHEMBL6735619 | 0.78 | TSHR (0.37) | TSHRCA2CA1LMNAUSP2 | |
| SCHEMBL6741981 | 0.77 | — | — | |
| SCHEMBL6739808 | 0.77 | ALDH1A1 (0.42) | TSHRCA2CA1LMNAUSP2 | |
| SCHEMBL27513922 | 0.77 | LMNA (0.42) | TSHRCA2CA1LMNAUSP2 | |
| SCHEMBL19746179 | 0.77 | MMP2 (0.36) | TSHRCA2CA1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048815-A1 | Low-molecular serine proteases inhibitors comprising polyhydroxy-alkyl and polyhydroxy-cycloalkyl radicals | ABBOTT GMBH & CO. KG (DE) | 2004-03-11 | — | — | US | disclosed |
| US-20040043903-A1 | Herbicides; applying to plants | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-04 | — | — | US | disclosed |
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
| US-20030216257-A1 | 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | DDT, HAX1, SULT1E1 | TSHR 762/4885CA2 511/4885CA1 2224/4885 |
| US-20040043903-A1 | Herbicides; applying to plants | DDT, DRD1, DRD4 | TSHR 1003/4885CA2 220/4885CA1 1441/4885 |
| US-20040048815-A1 | Low-molecular serine proteases inhibitors comprising polyhydroxy-alkyl and polyhydroxy-cycloalkyl radicals | F2R, C1R, PRSS1 | TSHR 797/4885CA2 727/4885CA1 558/4885 |
| US-20030216257-A1 | 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides | CYP1B1, DDT, CYP1A1 | TSHR 706/4885CA2 1233/4885CA1 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.