SCHEMBL6735667

SCHEMBL6735667

CN(c1ccc(C(=O)c2ccc(N(C)C(C)(C)C)cc2)cc1)C(C)(C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.61
ALDH1A1 P00352 3/20 0.61
MAPT P10636 3/20 0.61
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
LMNA P02545 2/20 0.44
SRD5A2 P31213 3/20 0.44
ELANE P08246 4/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
HDAC1 Q13547 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
NOTUM Q6P988 1/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SIRT1 Q96EB6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16730046 0.85 NPC1 (0.52) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL17036671 0.83 PARP10 (0.44) HPGDALDH1A1MAPTHDAC1HDAC6
SCHEMBL18098046 0.83 ALDH1A1 (0.42) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL126012 0.81 ALDH1A1 (0.44) HPGDALDH1A1MAPTMEN1TP53
SCHEMBL10294111 0.80 HDAC6 (0.52) HPGDALDH1A1HTTHDAC1HDAC6
SCHEMBL1829849 0.80 HPGD (0.58) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL10062370 0.78 HPGD (0.56) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL10294126 0.77 RAB9A (0.55) HPGDMAPTNPC1RAB9ALMNA
SCHEMBL274966 0.77 ALDH1A1 (1.00) HPGDALDH1A1MAPTNPC1RAB9A
Michler'S Ketone SCHEMBL36517 0.77 ALDH1A1 (1.00) HPGDALDH1A1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040054244-A1 Process of quadricyclane production EXCITON, INC. 2004-03-18 US claimed
US-20040031675-A1 Process of quadricyclane production EXCITON, INC. 2004-02-19 US disclosed
US-6635152-B1 Process of driving a non-polymerization solution-phase photochemical transformation EXCITON, INC. 2003-10-21 US disclosed