SCHEMBL10062370

SCHEMBL10062370

CC(C)(C)N(O)c1ccc(C(=O)c2ccc(N(O)C(C)(C)C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.56
ALDH1A1 P00352 3/20 0.56
MAPT P10636 2/20 0.56
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
LMNA P02545 2/20 0.44
SRD5A2 P31213 3/20 0.44
ELANE P08246 4/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
SIRT1 Q96EB6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10440811 0.88 HPGD (0.44) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL1829849 0.80 HPGD (0.58) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL6735667 0.78 HPGD (0.61) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL18747584 0.75 ESR1 (0.31) ESR1ESR2
SCHEMBL14372105 0.75 ALDH1A1 (0.46) ALDH1A1MAPTRAB9ALMNA
SCHEMBL329718 0.74 HPGD (0.63) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL20650991 0.73 ALDH1A1 (0.48) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL13813888 0.73 LMNA (0.48) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL23355253 0.73 ELANE (0.55) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL931848 0.72 MEN1 (0.42) HPGDALDH1A1MAPTNPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729532-B2 Light-absorbing material and photoelectric conversion element PANASONIC CORPORATION (JP) 2014-05-20 US disclosed
US-8729532-B2 Light-absorbing material and photoelectric conversion element PANASONIC CORPORATION (JP) 2014-05-20 US disclosed
US-20120181516-A1 LIGHT-ABSORBING MATERIAL AND PHOTOELECTRIC CONVERSION ELEMENT PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2012-07-19 US disclosed
US-20120181516-A1 LIGHT-ABSORBING MATERIAL AND PHOTOELECTRIC CONVERSION ELEMENT PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2012-07-19 US disclosed
EP-2433989-A1 LIGHT-ABSORBING MATERIAL AND PHOTOELECTRIC CONVERSION ELEMENT Panasonic Corporation (JP) 2012-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120181516-A1 LIGHT-ABSORBING MATERIAL AND PHOTOELECTRIC CONVERSION ELEMENT PPOX, CRY1, CYBA HPGD 567/4885ALDH1A1 110/4885MAPT 3623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.