Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738449 | 1.00 | KCNH2 (0.51) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6738998 | 1.00 | KCNH2 (0.51) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6735514 | 0.95 | KCNH2 (0.48) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6739623 | 0.95 | KCNH2 (0.48) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6739920 | 0.93 | MGLL (0.50) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6734797 | 0.92 | KCNH2 (0.50) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6739387 | 0.92 | KCNH2 (0.50) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6742834 | 0.92 | KCNH2 (0.50) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7478649 | 0.91 | KCNH2 (0.49) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6738303 | 0.91 | KCNH2 (0.49) | KCNH2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229900-A1 | Bispidine compounds useful in the treatment of cardiac arrythmias | ASTRAZENECA AB (SE) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229900-A1 | Bispidine compounds useful in the treatment of cardiac arrythmias | ADRA1B, ADRB2, ADRA1D | KCNH2 13/4885KDM4E 4541/4885ALDH1A1 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.