Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 10/20 | 0.47 |
| ▸ | CTSS | P25774 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 7/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063157 | 0.91 | CTSL (0.43) | ALDH1A1HPGDCTSLCTSSCTSB | |
| SCHEMBL6744804 | 0.88 | CTSL (0.46) | ALDH1A1CTSLCTSSCTSBITGAV | |
| SCHEMBL6740637 | 0.88 | CTSL (0.46) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6740731 | 0.88 | CTSL (0.46) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6741598 | 0.88 | CTSL (0.46) | CTSLCTSSCTSBITGAVCTSK | |
| SCHEMBL6740031 | 0.88 | CTSL (0.46) | CTSLCTSSCTSBITGAVCTSK | |
| SCHEMBL6061910 | 0.87 | CTSL (0.56) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7656140 | 0.86 | ITGAV (0.48) | ALDH1A1HPGDCTSLCTSSCTSB | |
| SCHEMBL6737517 | 0.85 | CTSL (0.49) | ALDH1A1CTSLCTSSCTSBCTSK | |
| SCHEMBL7661877 | 0.85 | CTSL (0.43) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | AXYS PHARMACEUTICALS, INC. | 2004-01-22 | — | — | US | disclosed |
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | CTSS, CTSB, CTSE | ALDH1A1 4044/4885HPGD 1593/4885CTSL 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.