Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737805 | 0.78 | CTSS (0.66) | CTSSCTSK | |
| SCHEMBL6737806 | 0.78 | CTSS (0.66) | CTSSCTSK | |
| SCHEMBL5517777 | 0.76 | CTSS (0.48) | CTSSHTTCTSK | |
| SCHEMBL5520661 | 0.73 | CTSS (0.46) | CTSSCTSKPKM | |
| SCHEMBL5523888 | 0.72 | CTSS (0.52) | CTSSHTTCTSKALDH1A1PKM | |
| SCHEMBL5521867 | 0.72 | ADRB1 (0.47) | CTSSCTSK | |
| SCHEMBL5534198 | 0.71 | CTSS (0.42) | CTSSCTSKALDH1A1 | |
| SCHEMBL5530353 | 0.70 | CTSL (0.49) | CTSSCTSKSMN1; SMN2 | |
| SCHEMBL5518353 | 0.70 | CTSS (0.52) | CTSSHTTCTSK | |
| SCHEMBL5523347 | 0.69 | MAPT (0.51) | CTSSHTTCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | AXYS PHARMACEUTICALS, INC. | 2004-01-22 | — | — | US | disclosed |
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | CTSS, CTSB, CTSE | CTSS 1/4885HTT 767/4885CTSK 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.