SCHEMBL6740158

SCHEMBL6740158

CCCOc1c(OC)cc(C)c(C(=O)c2c(OC)ccc(Cl)c2C)c1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 7/20 0.38
L3MBTL1 Q9Y468 6/20 0.38
GAA P10253 3/20 0.38
RAB9A P51151 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38
TUBA1A Q71U36 1/20 0.38
TUBA1C Q9BQE3 1/20 0.38
TUBB6 Q9BUF5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6743080 0.91 PDE4D (0.42) ALDH1A1SMN1; SMN2MAPTL3MBTL1GAA
SCHEMBL7602880 0.90 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2MAPTL3MBTL1GAA
SCHEMBL3767546 0.88 TOP1 (0.40) ALDH1A1MAPTKDM4ETUBB4ATUBB
SCHEMBL7524397 0.84 TUBB4A (0.38) ALDH1A1MAPTGAAKDM4ETUBB4A
SCHEMBL6740740 0.83 MEN1 (0.39) ALDH1A1SMN1; SMN2L3MBTL1GAARAB9A
SCHEMBL5610704 0.81 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MAPTRAB9AKDM4E
SCHEMBL6149687 0.81 RAB9A (0.42) ALDH1A1SMN1; SMN2MAPTL3MBTL1GAA
SCHEMBL7602621 0.81 MEN1 (0.41) MEN1KMT2A
SCHEMBL7525724 0.81 MAPT (0.41) ALDH1A1SMN1; SMN2MAPTRAB9AKDM4E
SCHEMBL6738733 0.80 ALDH1A1 (0.40) ALDH1A1MAPTGAAKDM4ETUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689776-B2 APPLYING TO THE CROP PLANTS BEING INFESTED WITH FUNGAL DISEASE, A BIPHENOXY COMPOUND IN ASSOCIATION WITH STROBILURIN OR CYANOIMIDAZOLE, OR CARBONIC ACID AMIDE SYNGENTA CROP PROTECTION, INC. 2004-02-10 US claimed
EP-1189508-B1 FUNGICIDAL COMPOSITIONS BAYER CROPSCIENCE AG (DE) 2003-10-08 EP claimed
EP-1185173-B1 FUNGICIDAL COMBINATIONS SYNGENTA PARTICIPATIONS AG (CH) 2003-05-28 EP claimed
US-6472428-B1 Fungicidal compositions BAYER AKTIENGESELLSCHAFT (DE) 2002-10-29 US claimed
US-20020107246-A1 Fungicidal combinations SYNGENTA CROP PROTECTION, INC. 2002-08-08 US claimed
EP-1189508-A1 FUNGICIDAL COMPOSITIONS Bayer Aktiengesellschaft (DE) 2002-03-27 EP claimed
EP-1185173-A1 FUNGICIDAL COMBINATIONS Syngenta Participations AG (CH) 2002-03-13 EP claimed
EP-0897904-B1 Fungicidal 2-methoxybenzophenones BASF AG (DE) 2002-02-20 EP claimed
WO-2000076317-A1 FUNGICIDAL COMBINATIONS SYNGENTA PARTICIPATIONS AG (CH) 2000-12-21 WO claimed
WO-2000072677-A1 FUNGICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (CH) 2000-12-07 WO claimed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP claimed
US-6790851-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, INC. 2004-09-14 US disclosed
US-6689776-B2 APPLYING TO THE CROP PLANTS BEING INFESTED WITH FUNGAL DISEASE, A BIPHENOXY COMPOUND IN ASSOCIATION WITH STROBILURIN OR CYANOIMIDAZOLE, OR CARBONIC ACID AMIDE SYNGENTA CROP PROTECTION, INC. 2004-02-10 US disclosed
EP-1278414-B1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2003-12-17 EP disclosed
EP-1189508-B1 FUNGICIDAL COMPOSITIONS BAYER CROPSCIENCE AG (DE) 2003-10-08 EP disclosed
WO-2001080643-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2001-11-01 WO disclosed
WO-2000076317-A1 FUNGICIDAL COMBINATIONS SYNGENTA PARTICIPATIONS AG (CH) 2000-12-21 WO disclosed
WO-2000072677-A1 FUNGICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (CH) 2000-12-07 WO disclosed
US-6001883-A SUBSTITUTED BENZOPHENONES OF GIVEN FORMULA, SUCH AS 6,6'-DIMETHYL-2,2',3',4'-TETRAMETHOXY-5-TRIFLUOROMETHYL-BENZOPHENONE; HIGHLY SYSTEMIC FUNGICIDES; CONTROLLING FUNGAL DISEASE SUCH AS POWDERY MILDEW IN PLANTS AMERICAN CYANAMID COMPANY (US) 1999-12-14 US disclosed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107246-A1 Fungicidal combinations CBR1, CBR3, CYP4B1 ALDH1A1 1052/4885SMN1; SMN2 3433/4885MAPT 4768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.