SCHEMBL6740740

SCHEMBL6740740

CCCCOc1c(OC)c(OC)cc(C)c1C(=O)c1c(C)ccc(Cl)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
THRB P10828 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.37
RAB9A P51151 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6740826 0.90 MEN1 (0.41) MEN1KMT2ATHRBL3MBTL1PDE4B
SCHEMBL6738733 0.87 ALDH1A1 (0.40) MEN1KMT2ACYP1A2HPGDCYP2C19
SCHEMBL6737783 0.87 SMN1; SMN2 (0.40) MEN1KMT2ATHRBSMN1; SMN2HPGD
SCHEMBL6150070 0.86 L3MBTL1 (0.43) MEN1KMT2ASMN1; SMN2NPC1HPGD
SCHEMBL7518830 0.84 L3MBTL1 (0.41) MEN1KMT2ASMN1; SMN2NPC1HPGD
SCHEMBL6149703 0.83 L3MBTL1 (0.42) MEN1KMT2ATHRBHPGDRAB9A
SCHEMBL6740158 0.83 ALDH1A1 (0.39) MEN1KMT2ASMN1; SMN2CYP2C9HPGD
SCHEMBL6741216 0.83 LMNA (0.39) MEN1KMT2ATHRBSMN1; SMN2NPC1
SCHEMBL6150124 0.83 L3MBTL1 (0.43) MEN1KMT2ASMN1; SMN2NPC1CYP1A2
SCHEMBL7522504 0.83 KCNB1 (0.42) MEN1KMT2ATHRBSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689776-B2 APPLYING TO THE CROP PLANTS BEING INFESTED WITH FUNGAL DISEASE, A BIPHENOXY COMPOUND IN ASSOCIATION WITH STROBILURIN OR CYANOIMIDAZOLE, OR CARBONIC ACID AMIDE SYNGENTA CROP PROTECTION, INC. 2004-02-10 US claimed
EP-1185173-B1 FUNGICIDAL COMBINATIONS SYNGENTA PARTICIPATIONS AG (CH) 2003-05-28 EP claimed
EP-0899255-B1 Fungicidal 2,6,6'-trimethylbenzophenones BASF AG (DE) 2003-04-02 EP claimed
EP-1185176-B1 FUNGICIDAL COMPOSITIONS BAYER CROPSCIENCE AG (DE) 2003-03-05 EP claimed
US-6472429-B1 Fungicidal compositions BAYER AKTIENGESELLSCHAFT (DE) 2002-10-29 US claimed
US-20020107246-A1 Fungicidal combinations SYNGENTA CROP PROTECTION, INC. 2002-08-08 US claimed
EP-1185173-A1 FUNGICIDAL COMBINATIONS Syngenta Participations AG (CH) 2002-03-13 EP claimed
EP-1185176-A1 FUNGICIDAL COMPOSITIONS Bayer Aktiengesellschaft (DE) 2002-03-13 EP claimed
US-6242498-B1 NONPHYTOTOXIC BASF AKTIENGESELLSCHAFT 2001-06-05 US claimed
WO-2000076317-A1 FUNGICIDAL COMBINATIONS SYNGENTA PARTICIPATIONS AG (CH) 2000-12-21 WO claimed
WO-2000072678-A1 FUNGICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2000-12-07 WO claimed
EP-0899255-A2 Fungicidal 2,6,6'-trimethylbenzophenones American Cyanamid Company (US) 1999-03-03 EP claimed
US-6790851-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, INC. 2004-09-14 US disclosed
US-6689776-B2 APPLYING TO THE CROP PLANTS BEING INFESTED WITH FUNGAL DISEASE, A BIPHENOXY COMPOUND IN ASSOCIATION WITH STROBILURIN OR CYANOIMIDAZOLE, OR CARBONIC ACID AMIDE SYNGENTA CROP PROTECTION, INC. 2004-02-10 US disclosed
EP-1278414-B1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2003-12-17 EP disclosed
US-20030166669-A1 Fungicidal compositions SYNGENTA CROP PROTECTION, INC. 2003-09-04 US disclosed
WO-2001080643-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2001-11-01 WO disclosed
US-6242498-B1 NONPHYTOTOXIC BASF AKTIENGESELLSCHAFT 2001-06-05 US disclosed
WO-2000076317-A1 FUNGICIDAL COMBINATIONS SYNGENTA PARTICIPATIONS AG (CH) 2000-12-21 WO disclosed
EP-0899255-A2 Fungicidal 2,6,6'-trimethylbenzophenones American Cyanamid Company (US) 1999-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107246-A1 Fungicidal combinations CBR1, CBR3, CYP4B1 MEN1 2743/4885KMT2A 1293/4885THRB 3305/4885
US-20030166669-A1 Fungicidal compositions CBR1, CBR3, CYP1B1 MEN1 2693/4885KMT2A 2754/4885THRB 3621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.