Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740158 | 0.90 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KDM4EMAPTL3MBTL1 | |
| SCHEMBL6743080 | 0.81 | PDE4D (0.42) | ALDH1A1SMN1; SMN2KDM4EMAPTL3MBTL1 | |
| SCHEMBL7525724 | 0.80 | MAPT (0.41) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL3767546 | 0.80 | TOP1 (0.40) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL6740740 | 0.78 | MEN1 (0.39) | ALDH1A1SMN1; SMN2L3MBTL1HPGDRAB9A | |
| SCHEMBL7524397 | 0.76 | TUBB4A (0.38) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL6149687 | 0.76 | RAB9A (0.42) | ALDH1A1SMN1; SMN2KDM4EMAPTL3MBTL1 | |
| SCHEMBL5610704 | 0.73 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL1850970 | 0.72 | MAPT (0.39) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL7598060 | 0.72 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155518-A1 | Method of detecting compounds that control fungal diseases via effects on sporulation | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | US | disclosed |