Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572577 | 0.84 | — | — | |
| SCHEMBL5969404 | 0.82 | TSHR (0.41) | TSHRALDH1A1FAAHLMNAADH1B | |
| SCHEMBL10893586 | 0.81 | LMNA (0.42) | TSHRALDH1A1LMNADNM1FFAR1 | |
| SCHEMBL132565 | 0.81 | LMNA (0.42) | TSHRALDH1A1LMNADNM1FFAR1 | |
| SCHEMBL11396945 | 0.77 | LMNA (0.39) | TSHRALDH1A1LMNADNM1FFAR1 | |
| SCHEMBL11395225 | 0.77 | DNM1 (0.42) | TSHRALDH1A1LMNADNM1ACE2 | |
| SCHEMBL3481725 | 0.74 | OPRM1 (0.39) | TSHRALDH1A1LMNADNM1FFAR1 | |
| SCHEMBL11831237 | 0.74 | TSHR (0.44) | TSHRALDH1A1FAAHLMNAADH1B | |
| SCHEMBL25182517 | 0.73 | LMNA (0.50) | TSHRALDH1A1FAAHLMNAADH1B | |
| SCHEMBL9445614 | 0.73 | LMNA (0.50) | TSHRALDH1A1FAAHLMNAADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794044-B2 | STABILITY AND DURABILITY OF ORGANOSILANES ON THE SURFACES OF SILICA PACKING | SELERITY TECHNOLOGIES, INC. | 2004-09-21 | — | — | US | disclosed |
| US-20020146574-A1 | Chromatographic packing materials and methods of making and using such packing materials | SELERITY TECHNOLOGIES, INC. | 2002-10-10 | — | — | US | disclosed |