SCHEMBL6740575

SCHEMBL6740575

FC(F)(F)c1snc(-c2ccc(Cl)cc2Cl)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
AHR P35869 1/20 0.40
S1PR1 P21453 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
DPP4 P27487 2/20 0.38
HSD11B1 P28845 2/20 0.38
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
USP2 O75604 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6741167 0.77 GAA (0.32) GAA
SCHEMBL6740040 0.71 ALPL (0.44) ALDH1A1AHRRAB9AKDM4EKMT2A
SCHEMBL6739538 0.69 PPOX (0.35)
SCHEMBL6740540 0.69 HSP90AA1 (0.36) ALDH1A1FFAR4KDM4EGAAHPGD
SCHEMBL6985020 0.68 CNR1 (0.40) KDM4EMAPT
SCHEMBL6735476 0.67 ALPL (0.49) ALDH1A1RAB9AKDM4EHPGDMAPT
SCHEMBL6987268 0.65 ALPL (0.41) KDM4EMAPTKMT2A
SCHEMBL6735462 0.65
SCHEMBL19643160 0.65 FFAR4 (0.43) ALDH1A1FFAR4RAB9AKDM4EGAA
SCHEMBL464507 0.64 AHR (0.64) ALDH1A1AHRHSD11B1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040023807-A1 3-Arylisothiazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed
EP-1289970-A1 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2003-03-12 EP disclosed
WO-2001087863-A1 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-11-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023807-A1 3-Arylisothiazoles and their use as herbicides DDT, HAX1, SULT1E1 ALDH1A1 142/4885AHR 157/4885S1PR1 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.