SCHEMBL674067

SCHEMBL674067

COC(=S)c1cccc2nnsc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 10/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
NPC1 O15118 3/20 0.35
TP53 P04637 2/20 0.35
LMNA P02545 2/20 0.33
THRB P10828 1/20 0.33
PPARG P37231 1/20 0.30
NCOA2 Q15596 1/20 0.30
NCOA1 Q15788 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NCOA3 Q9Y6Q9 1/20 0.30
POLB P06746 2/20 0.30
MALT1 Q9UDY8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9087223 0.83 MAPT (0.33) RAB9AALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL9368398 0.83 MAPT (0.38) RAB9AKMT2AMEN1ALDH1A1MAPT
SCHEMBL395801 0.81 TP53 (0.31) ALDH1A1MAPTSMN1; SMN2TP53
SCHEMBL31151370 0.81 TP53 (0.31) ALDH1A1MAPTSMN1; SMN2TP53
SCHEMBL9363650 0.79 ASH1L (0.33) MAPTSMN1; SMN2TP53
SCHEMBL9426367 0.79 TP53 (0.32) RAB9AKMT2AMEN1ALDH1A1MAPT
1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL8588144 0.77 MAPT (0.45) RAB9AKMT2AMEN1ALDH1A1MAPT
SCHEMBL9087937 0.76 ALDH1A1 (0.33) ALDH1A1MAPTSMN1; SMN2TP53
SCHEMBL8051642 0.76 MAPT (0.45) RAB9AKMT2AMEN1ALDH1A1MAPT
SCHEMBL6971403 0.75 THRB (0.51) RAB9AALDH1A1MAPTSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100197495-A1 Synergistic Mixtures and/or Compositions With a High Fungicidal Activity ISAGRO S.P.A. (IT) 2010-08-05 US claimed
US-20060159772-A1 Fungicidal compositions ISAGRO S.P.A. (IT) 2006-07-20 US claimed
EP-1565057-A2 FUNGICIDAL COMPOSITIONS CONTAINING AT LEAST ONE SALT OF PHOSPHOROUS ACID AND AT LEAST A SECOND FUNGICIDAL COMPONENT ISAGRO S.p.A. (IT) 2005-08-24 EP claimed
WO-2004047540-A2 FUNGICIDAL COMPOSITIONS CONTAINING AT LEAST ONE SALT OF PHOSPHOROUS ACID AND AT LEAST A SECOND FUNGICIDAL COMPONENT ISAGRO S.P.A. (IT) 2004-06-10 WO claimed
WO-2023215837-A2 COMPOSITIONS FOR DELIVERY OF AGENTS INTO PLANT CELLS OHIO STATE INNOVATION FOUNDATION (US) 2023-11-09 WO disclosed
WO-2023168484-A1 \"COMPOUNDS AND METHODS\ DemAgtech Pty Ltd (AU) 2023-09-14 WO disclosed
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2022-06-02 US disclosed
US-10899932-B2 Non-amphoteric, quaternisable and water-soluble polymers for modifying the surface charge of solid particles BASF SE (DE) 2021-01-26 US disclosed
US-10759767-B2 Compositions comprising a triazole compound BASF Agro B.V. (NL) 2020-09-01 US disclosed
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 EP disclosed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 EP disclosed
EP-3498098-A1 COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2019-06-19 EP disclosed
WO-2007003603-A2 FUNGICIDE MIXTURES BASED ON 3-MONOSUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYL AMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 WO disclosed
WO-2007000462-A1 FUNGICIDE MIXTURES BASED ON 2,4-DISUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-04 WO disclosed
EP-1732388-A1 TERNARY FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2006-12-20 EP disclosed
US-20060159772-A1 Fungicidal compositions ISAGRO S.P.A. (IT) 2006-07-20 US disclosed
WO-2006069699-A1 FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2006-07-06 WO disclosed
WO-2006015728-A1 FUNGICIDAL SYNERGISTIC MIXTURES MADE OF TRIAZOLOPYRMIDINE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2006-02-16 WO disclosed
WO-2005094583-A1 TERNARY FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2005-10-13 WO disclosed
WO-2005026139-A1 NEMATICIDAL DIFLUOROALKENES BAYER CROPSCIENCE AG (DE) 2005-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST P2RX7, CAT, PDE8A RAB9A 120/4885KMT2A 1069/4885MEN1 2904/4885
US-10759767-B2 Compositions comprising a triazole compound CYP1B1, CYP3A5, CYP4B1 RAB9A 3394/4885KMT2A 2664/4885MEN1 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.