Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GPR6 | P46095 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111851 | 0.82 | PTGS1 (0.56) | MEN1KMT2ACES2KCNK3RAB9A | |
| SCHEMBL5847023 | 0.79 | ROCK2 (0.47) | HDAC1MEN1KMT2AALDH1A1 | |
| SCHEMBL5846937 | 0.77 | RAB9A (0.45) | HDAC1MEN1KMT2ACES2CES1 | |
| SCHEMBL5847488 | 0.76 | HDAC1 (0.50) | HDAC1HDAC6KCNK3ALPLKDM4E | |
| SCHEMBL7114643 | 0.75 | OGG1 (0.47) | MEN1KMT2ACES2CES1L3MBTL1 | |
| SCHEMBL5847247 | 0.73 | ALDH1A1 (0.33) | NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6744941 | 0.73 | POLB (0.46) | KMT2AKCNK3L3MBTL1NPC1RAB9A | |
| SCHEMBL5846615 | 0.73 | CTSD (0.45) | HDAC1HDAC6MEN1KMT2AL3MBTL1 | |
| SCHEMBL6737821 | 0.73 | PTGS1 (0.51) | HDAC1KCNK3NPC1RAB9AKCNK9 | |
| SCHEMBL5846767 | 0.72 | HDAC6 (0.47) | HDAC1HDAC6MEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686484-B2 | ANTICOAGULANTS; SERINE PROTEASE INHIBITOR | PHARMACIA CORPORATION | 2004-02-03 | — | — | US | claimed |
| EP-1014183-B1 | Colour photographic recording material | AGFA GEVAERT (BE) | 2003-10-08 | — | — | EP | disclosed |
| EP-1014183-A2 | Colour photographic recording material | Agfa-Gevaert AG (DE) | 2000-06-28 | — | — | EP | disclosed |