SCHEMBL6741095

SCHEMBL6741095

Nc1cccc(Oc2ccccc2S(=O)(=O)c2ccccc2Oc2cccc(N)c2C(=O)O)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
HTR6 P50406 2/20 0.41
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CDC25B P30305 1/20 0.38
KYNU Q16719 2/20 0.37
CYP2C9 P11712 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
METAP2 P50579 1/20 0.36
CASP1 P29466 3/20 0.36
TTR P02766 1/20 0.36
MMP2 P08253 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7713669 0.85 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL28597961 0.83 HTT (0.45) HTR6CA12CA1CA2CA7
SCHEMBL29736476 0.83 HTT (0.45) HTR6CA12CA1CA2CA7
SCHEMBL29913887 0.80 GAA (0.59) GAAHTR6CA12CA1CA2
SCHEMBL7713661 0.80 GAA (0.54) GAAHTR6CA12CA1CA2
SCHEMBL461323 0.80 GAA (0.59) GAAHTR6CA12CA1CA2
SCHEMBL6735351 0.80 GAA (0.50) GAAHTR6CA12CA1CA2
Ammonia Solution, Strong SCHEMBL23003834 0.79 GAA (0.57) GAAHTR6CA12CA1CA2
SCHEMBL28415540 0.77 NCOA1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL7601905 0.77 HTR6 (0.50) HTR6CA1CA2MMP2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686106-B2 POLYIMIDESILOXANE COPOLYMERS UBE INDUSTRIES, LTD. (JP) 2004-02-03 US disclosed
US-20020001763-A1 Photosensitive resin compositions, insulating films, and processes for formation of the films UBE INDUSTRIES, LTD. 2002-01-03 US disclosed