SCHEMBL6741499

SCHEMBL6741499

OB(O)c1cc(F)c(OC(F)(F)F)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.34
EPHX2 P34913 1/20 0.32
ABL1 P00519 1/20 0.31
ENPP2 Q13822 2/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3771015 0.78 ENPP2 (0.41) ENPP2CA1CA2
SCHEMBL28225174 0.78 MGLL (0.33) MGLL
SCHEMBL28838309 0.78 FFAR1 (0.31) EPHX2
SCHEMBL29953916 0.76 ENPP2 (0.33) MGLLENPP2CA1CA2
SCHEMBL760695 0.76 TAAR1 (0.37) EPHX2CA1
SCHEMBL12736297 0.75 GPR3 (0.33) EPHX2
SCHEMBL491621 0.75 EPHX2 (0.50) MGLLEPHX2ABL1CA1CA2
SCHEMBL17404934 0.75 MAPT (0.36) MGLL
SCHEMBL12247265 0.72 ABL1 (0.35) MGLLEPHX2ABL1ENPP2
SCHEMBL7435094 0.72 CYP3A4 (0.42) ENPP2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114256431-B Material for organic electroluminescent element, and consumer product 上海八亿时空先进材料有限公司 2025-02-25 CN disclosed
CN-114256431-A Material for organic electroluminescent element, and consumer product 上海八亿时空先进材料有限公司 2022-03-29 CN disclosed
US-20210340121-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2021-11-04 US disclosed
US-11008302-B2 Substituted pyridine and pyrimidines and their use as GluN2B receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2021-05-18 US disclosed
EP-3774732-A2 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS Janssen Pharmaceutica NV (BE) 2021-02-17 EP disclosed
WO-2019193516-A2 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2019-10-10 WO disclosed
US-20190308950-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2019-10-10 US disclosed
US-6682785-B2 A FLUOROANTHRACENE COMPOUNDS; HEAT RESISTANCE, RADIATION RESISTANCE, PHOTOSTABILITY CLARIANT FINANCE (BVI) LIMITED (VG) 2004-01-27 US disclosed
US-20030118749-A1 A fluoroanthracene compounds; heat resistance, radiation resistance, photostability CLARIANT INTERNATIONAL LTD. 2003-06-26 US disclosed
US-6329027-B1 Chlorobenzene derivatives, liquid-crystal composition, and liquid-crystal display elements CHISSO CORPORATION (JP) 2001-12-11 US disclosed
EP-0959060-A1 CHLOROBENZENE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENTS CHISSO CORPORATION (JP) 1999-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190308950-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS GRIN2B, GRIN2A, GRIN3B MGLL 4781/4885EPHX2 2087/4885ABL1 733/4885
US-20030118749-A1 A fluoroanthracene compounds; heat resistance, radiation resistance, photostability HSF1, ABCC1, FLNA MGLL 1872/4885EPHX2 4298/4885ABL1 801/4885
US-20210340121-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS GRIN2B, GRIN2A, GRIN3B MGLL 4781/4885EPHX2 2087/4885ABL1 733/4885
US-11008302-B2 Substituted pyridine and pyrimidines and their use as GluN2B receptor modulators GRIN2B, GRIN2A, GRIN3B MGLL 4789/4885EPHX2 1966/4885ABL1 739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.