Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29320324 | 0.87 | AURKA (0.41) | CA12CA1CA9TDP1AURKA | |
| SCHEMBL31256373 | 0.86 | ALOX5 (0.33) | TAAR1CA12CA1CA9AURKA | |
| SCHEMBL18559875 | 0.80 | TAAR1 (0.33) | TAAR1CA12CA1CA9TDP1 | |
| SCHEMBL12736297 | 0.80 | GPR3 (0.33) | EPHX2PDE2AGPR3 | |
| SCHEMBL23484287 | 0.78 | TDP1 (0.48) | CA12CA1CA9TDP1AURKA | |
| SCHEMBL6558034 | 0.76 | MAPT (0.36) | MAPTEPHX2PDE2AGPR3 | |
| SCHEMBL3683516 | 0.76 | GPR3 (0.31) | EPHX2GPR3 | |
| SCHEMBL7723333 | 0.76 | GPR3 (0.31) | EPHX2PDE2AGPR3 | |
| SCHEMBL10052628 | 0.76 | ACHE (0.36) | MAPTEPHX2PDE2AFFAR4GPR3 | |
| SCHEMBL7772178 | 0.76 | GRIN2B (0.33) | EPHX2FFAR1FFAR4GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263749-B1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2025-06-18 | — | — | EP | disclosed |
| US-20250134907-A1 | FUSED DIAZEPINES AS AGONISTS OF THE INSULIN-LIKE 3 (INSL3) PEPTIDE RECEPTOR RXFP2 AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-05-01 | — | — | US | disclosed |
| EP-4476222-A1 | FUSED DIAZEPINES AS AGONISTS OF THE INSULIN-LIKE 3 (INSL3) PEPTIDE RECEPTOR RXFP2 AND METHODS OF USE THEREOF | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2024-12-18 | — | — | EP | disclosed |
| CN-117164436-A | Method for synthesizing polyfluorophenol by lanthanum cerium copper catalysis | 浙江大学衢州研究院 | 2023-12-05 | — | — | CN | disclosed |
| CN-117024254-A | Synthesis method of polyfluorophenol | 浙江大学衢州研究院 | 2023-11-10 | — | — | CN | disclosed |
| EP-4263749-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | Merck Patent GmbH (DE) | 2023-10-25 | — | — | EP | disclosed |
| CN-116670255-A | Dibenzofuran and dibenzothiophene derivatives | 默克专利股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023154197-A1 | FUSED DIAZEPINES AS AGONISTS OF THE INSULIN-LIKE 3 (INSL3) PEPTIDE RECEPTOR RXFP2 AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2022128847-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| US-11254647-B2 | Benzo-fused heterocyclic derivatives useful as agonists of GPR120 | JANSSEN PHARMACEUTICA NV (BE) | 2022-02-22 | — | — | US | disclosed |
| US-20060025615-A1 | Method for production naphthalene derivatives | MERCK PATENT GMBH (DE) | 2006-02-02 | — | — | US | disclosed |
| EP-1581469-A1 | METHOD FOR PRODUCING NAPHTHALENE DERIVATIVES | MERCK PATENT GmbH (DE) | 2005-10-05 | — | — | EP | disclosed |
| US-20040173776-A1 | for displays with very low threshold voltages and at the same time high values for the voltage holding ratio | MERCK PATENT GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| EP-1454975-A2 | Liquid crystalline medium | MERCK PATENT GmbH (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2004050594-A1 | METHOD FOR PRODUCING NAPHTHALENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-06-17 | — | — | WO | disclosed |
| US-6337034-B1 | COMPOUNDS HAVING WIDE TEMPERATURE RANGE OF LIQUID CRYSTAL PHASE, LOW VISCOSITY, LOW THRESHOLD VOLTAGE AND EXCELLENT STABILITY, WHICH ARE READILY MIXED WITH VARIOUS LIQUID CRYSTAL MATERIALS AND GOOD IN SOLUBILITY AT LOW TEMPERATURE | CHISSO CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0820976-B1 | FLUORINE-SUBSTITUTED LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORP (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-6051288-A | LARGE DIELECTRIC ANISOTROPY, SMALL CHANGE IN THRESHOLD VOLTAGE DEPENDING ON TEMPERATURE, AND AN IMPROVED SOLUBILITY TO OTHER LIQUID CRYSTAL MATERIALS AT LOW TEMPERATURES | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0885875-A1 | VINYLENE COMPOUNDS AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0820976-A1 | FLUORINE-SUBSTITUTED LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250134907-A1 | FUSED DIAZEPINES AS AGONISTS OF THE INSULIN-LIKE 3 (INSL3) PEPTIDE RECEPTOR RXFP2 AND METHODS OF USE THEREOF | RXFP3, RXFP4, RXFP2 | TAAR1 1588/4885CA12 2330/4885CA1 2587/4885 |
| US-20060025615-A1 | Method for production naphthalene derivatives | AOX1, AOC3, CBR3 | TAAR1 2102/4885CA12 1271/4885CA1 1248/4885 |
| US-11254647-B2 | Benzo-fused heterocyclic derivatives useful as agonists of GPR120 | GPR119, GPR180, GPR55 | TAAR1 294/4885CA12 4456/4885CA1 4805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.