Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 12/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859970 | 0.91 | HSD17B1 (0.52) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL673067 | 0.87 | ESR1 (0.57) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL16719493 | 0.84 | HSD17B1 (0.42) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL31418250 | 0.84 | HSD17B1 (0.42) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL672712 | 0.82 | ESR1 (0.46) | ESR1ESR2MEN1KMT2AABL1 | |
| SCHEMBL9941579 | 0.82 | ESR1 (0.56) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL595369 | 0.80 | PKM (0.44) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL6505461 | 0.80 | NR1H2 (0.41) | CYP1A2MEN1KMT2A | |
| SCHEMBL13411813 | 0.80 | ADH5 (0.36) | — | |
| SCHEMBL8257794 | 0.79 | CDK2 (0.45) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| WO-2012024495-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012024495-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | ABL1, ABL2, TST | HSD17B1 3698/4885HSD17B2 3590/4885CYP3A4 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.