SCHEMBL674157

SCHEMBL674157

O=C(OBr)c1ccccc1C(=O)OBr

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
ALDH1A1 P00352 6/20 0.46
ALOX15 P16050 2/20 0.46
CYP3A4 P08684 2/20 0.45
NPC1 O15118 1/20 0.45
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 3/20 0.43
TP53 P04637 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 2/20 0.41
CFTR P13569 1/20 0.41
HPGD P15428 1/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
ATM Q13315 1/20 0.40
F2 P00734 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38657491 1.00 TSHR (0.50) TSHRALDH1A1ALOX15CYP3A4NPC1
SCHEMBL5973872 0.84 PTPN2 (0.51) TSHRALDH1A1ALOX15CYP3A4NPC1
SCHEMBL17219848 0.84 ALDH1A1 (0.64) TSHRALDH1A1ALOX15CYP3A4NPC1
SCHEMBL3930009 0.84 CES2 (0.58) ALDH1A1ALOX15NPC1TDP1L3MBTL1
SCHEMBL1851122 0.84 NPC1 (0.50) TSHRNPC1L3MBTL1LMNAHPGD
Methane SCHEMBL23161892 0.82 NPC1 (0.49) TSHRNPC1L3MBTL1LMNAHPGD
SCHEMBL8852648 0.80 HPGD (0.56) TSHRALDH1A1NPC1L3MBTL1MAPK1
SCHEMBL2727814 0.80 ALDH1A1 (0.46) TSHRALDH1A1ALOX15CYP3A4NPC1
SCHEMBL3807750 0.80 NR4A1 (0.59) ALDH1A1NPC1L3MBTL1MAPK1HPGD
SCHEMBL9756368 0.77 MYC (0.44) TSHRALDH1A1NPC1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110358066-A Organic synthesis type flame-retardant polycarbonate material and preparation method thereof 中北大学 2019-10-22 CN claimed
CN-109401309-A A kind of aromatic heterocyclic polymer resin of UV resistant high transparent and fire-retardant and preparation method thereof and application in fiber or film 刘文熙 2019-03-01 CN claimed
CN-109337050-A A kind of aromatic heterocyclic polymer resin of high intensity UV resistant high transparent and fire-retardant and preparation method thereof and application in fiber or film 潘鑫 2019-02-15 CN claimed
CN-109320703-A A kind of aromatic heterocyclic polymer resin that UV resistant is fire-retardant and preparation method thereof and application in fiber or film 刘文熙 2019-02-12 CN claimed
CN-109320924-A A kind of aromatic heterocyclic polymer film and its preparation method and application that high intensity UV resistant is fire-retardant 刘文熙 2019-02-12 CN claimed
CN-109306181-A A kind of aromatic heterocyclic polymer resin that UV resistant is fire-retardant and preparation method thereof and application in fiber or film 刘文熙 2019-02-05 CN claimed
CN-109306182-A A kind of aromatic heterocyclic polymer resin that high-strength and high-transparent is fire-retardant and preparation method thereof and application in fiber or film 刘文熙 2019-02-05 CN claimed
CN-109306183-A Fire-retardant aromatic heterocyclic polymer resin of a kind of high intensity UV resistant and preparation method thereof and application in fiber or film 王庭辉 2019-02-05 CN claimed
CN-109293899-A A kind of aromatic heterocyclic polymer resin of high-strength anti-flaming and preparation method thereof and application in fiber or film 潘鑫 2019-02-01 CN claimed
CN-109293895-A A kind of fire-retardant aromatic heterocyclic polymer resin and preparation method thereof and application in fiber or film 潘鑫 2019-02-01 CN claimed
CN-109293897-A A kind of aromatic heterocyclic polymer resin of high transparent and fire-retardant and preparation method thereof and application in fiber or film 王庭辉 2019-02-01 CN claimed
CN-109280382-A A kind of aromatic heterocyclic polymer resin of UV resistant high transparent and fire-retardant and preparation method thereof and application in fiber or film 王庭辉 2019-01-29 CN claimed
CN-109280381-A A kind of fire-retardant aromatic heterocyclic polymer resin and preparation method thereof and application in fiber or film 王庭辉 2019-01-29 CN claimed
CN-109280380-A A kind of aromatic heterocyclic polymer resin that high-strength and high-transparent is fire-retardant and preparation method thereof and application in fiber or film 刘文熙 2019-01-29 CN claimed
CN-110997795-B High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2022-10-04 CN disclosed
US-20220007648-A1 Biocidal Compound ZHANG XINGCHEN (US) 2022-01-13 US disclosed
CN-109716216-A photochromic lens and polymerizable composition 三井化学株式会社 2019-05-03 CN disclosed
CN-1149066-A Process for producing finished product of plastic lens MITSUI TOATSU CHEMICALS (JP) 1997-05-07 CN disclosed
CN-1098723-A Preparation has the method for high refractive index resins MITSUI TOATSU CHEMICALS (JP) 1995-02-15 CN disclosed
CN-1039429-A Resin having high refractive index, lens comprising the resin, and method for producing the lens MITSUI TOATSU CHEMICALS (JP) 1990-02-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220007648-A1 Biocidal Compound BPGM, ACMSD, PGM2 TSHR 3450/4885ALDH1A1 3415/4885ALOX15 4064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.