Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.59 |
| ▸ | IL1RN | P18510 | 1/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738009 | 0.86 | KEAP1 (0.53) | KMT2AMEN1ALDH1A1PKMKEAP1 | |
| SCHEMBL810795 | 0.80 | KMT2A (0.91) | KMT2AMEN1ALDH1A1PKMKEAP1 | |
| SCHEMBL9480255 | 0.80 | NR3C2 (0.70) | KMT2AMEN1ALDH1A1PKMKEAP1 | |
| SCHEMBL6741160 | 0.79 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1PKMKEAP1 | |
| SCHEMBL5718766 | 0.78 | ALDH1A1 (0.73) | KMT2AMEN1ALDH1A1PKMKEAP1 | |
| SCHEMBL9001182 | 0.77 | KMT2A (1.00) | KMT2AMEN1ALDH1A1PKMKEAP1 | |
| SCHEMBL25031372 | 0.76 | KEAP1 (1.00) | KMT2AMEN1ALDH1A1PKMKEAP1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 | 0.76 | KEAP1 (1.00) | KMT2AMEN1ALDH1A1PKMKEAP1 | |
| SCHEMBL9292268 | 0.76 | ALDH1A1 (0.94) | KMT2AMEN1ALDH1A1PKMHPGD | |
| SCHEMBL13167612 | 0.75 | KMT2A (0.80) | KMT2AMEN1ALDH1A1PKMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2004-04-01 | — | — | US | disclosed |
| EP-1322598-A1 | NITROSO DIPHENYLAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028820-A1 | NITROSO DIPHENYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | NQO2, SULT1A1, NAT1 | KMT2A 531/4885MEN1 3077/4885ALDH1A1 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.