Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677645 | 0.94 | PTGS2 (0.40) | PDE4BPDE4APDE4CPDE4DPOLB | |
| SCHEMBL7681363 | 0.90 | PTGS2 (0.41) | PDE4BPDE4APDE4CPDE4DL3MBTL1 | |
| SCHEMBL7685116 | 0.88 | ALDH1A1 (0.34) | PDE4BPDE4APDE4CPDE4DPOLB | |
| SCHEMBL7677539 | 0.87 | HPGD (0.39) | PDE4BPDE4APDE4CPDE4DPOLB | |
| SCHEMBL7683343 | 0.86 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DL3MBTL1 | |
| SCHEMBL7677655 | 0.86 | CNR2 (0.40) | PDE4BPDE4APDE4CPDE4DPTGS2 | |
| SCHEMBL7683047 | 0.85 | PDE4A (0.38) | PDE4BPDE4APDE4CPDE4DPOLB | |
| SCHEMBL7682738 | 0.85 | ALDH1A1 (0.37) | PDE4BPDE4APDE4CPDE4DL3MBTL1 | |
| SCHEMBL7680208 | 0.83 | PDE4A (0.38) | PDE4BPDE4APDE4CPDE4DPOLB | |
| SCHEMBL7676299 | 0.83 | TSHR (0.34) | POLBTDP1L3MBTL1PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |