Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177056 | 0.81 | ALDH1A1 (0.49) | ALDH1A1PKMLMNASMN1; SMN2KDM4E | |
| SCHEMBL24485536 | 0.80 | ALDH1A1 (0.48) | ALDH1A1PKMLMNASMN1; SMN2KDM4E | |
| SCHEMBL4179360 | 0.78 | SORT1 (0.51) | ALDH1A1PKMSORT1SMN1; SMN2KDM4E | |
| SCHEMBL7713824 | 0.78 | ALDH1A1 (0.56) | ALDH1A1PKMLMNASMN1; SMN2KDM4E | |
| SCHEMBL6742533 | 0.78 | ASPH (0.41) | NPC1RAB9A | |
| SCHEMBL31239091 | 0.77 | SMN1; SMN2 (0.52) | ALDH1A1PKMSORT1SMN1; SMN2KDM4E | |
| SCHEMBL29627103 | 0.77 | ALDH1A1 (0.48) | ALDH1A1PKMLMNASMN1; SMN2KDM4E | |
| SCHEMBL24485243 | 0.77 | ALDH1A1 (0.47) | ALDH1A1PKMLMNASMN1; SMN2KDM4E | |
| SCHEMBL6174846 | 0.77 | SMN1; SMN2 (0.52) | ALDH1A1PKMSORT1SMN1; SMN2KDM4E | |
| SCHEMBL4181900 | 0.77 | SORT1 (0.53) | ALDH1A1PKMLMNASORT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226127-B1 | SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-6849618-B2 | Uracil substituted phenyl sulfamoly carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20040220172-A1 | Herbicidal compositions for the desiccation/ defoliation of plants | CARLSEN MARIANNE | 2004-11-04 | — | — | US | disclosed |
| US-6689773-B2 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | disclosed |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CARLSEN MARIANNE (US) | 2003-12-04 | — | — | US | disclosed |
| US-6534492-B2 | Herbicidal phenylsulfamoyl carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-18 | — | — | US | disclosed |
| CN-1383425-A | Uracil substituted phenyl sulfamoyl carboxamides | BASF AG (DE) | 2002-12-04 | — | — | CN | disclosed |
| EP-1226127-A2 | URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-31 | — | — | EP | disclosed |
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) | 2002-04-18 | — | — | US | disclosed |
| EP-0851858-B1 | SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001083459-A2 | URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
| US-6010980-A | Substituted 2-phenylpyridines as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-04 | — | — | US | disclosed |
| CN-1196722-A | Substitued 2-phenylpyridines as herbicides | BASF AG (DE) | 1998-10-21 | — | — | CN | disclosed |
| EP-0851858-A1 | SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-08 | — | — | EP | disclosed |
| WO-1997011059-A1 | SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CCNH, CBR3, UNG | ALDH1A1 456/4885PKM 4431/4885LMNA 4185/4885 |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CCNH, CBR3, UNG | ALDH1A1 456/4885PKM 4431/4885LMNA 4185/4885 |
| US-20040220172-A1 | Herbicidal compositions for the desiccation/ defoliation of plants | CBR3, HDHD5, DDAH1 | ALDH1A1 246/4885PKM 4722/4885LMNA 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.