Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800291 | 0.90 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAKMT2AHPGD | |
| SCHEMBL1982730 | 0.89 | TSHR (0.63) | ALDH1A1SMN1; SMN2LMNAKMT2AHPGD | |
| SCHEMBL13461422 | 0.88 | PDK1 (0.50) | ALDH1A1SMN1; SMN2LMNAKMT2AHPGD | |
| SCHEMBL4641784 | 0.86 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNAKMT2AHPGD | |
| SCHEMBL7319750 | 0.86 | PRSS1 (0.66) | ALDH1A1SMN1; SMN2LMNAKMT2AHPGD | |
| SCHEMBL20285788 | 0.85 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AHPGD | |
| SCHEMBL4337680 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2APOLBMAPT | |
| SCHEMBL30825381 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2APOLBMAPT | |
| SCHEMBL28106211 | 0.85 | VCAM1 (0.61) | ALDH1A1SMN1; SMN2LMNAKMT2AHPGD | |
| SCHEMBL11803783 | 0.85 | POLB (0.51) | ALDH1A1SMN1; SMN2LMNAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181681-A | 2-Amino-4-ethynylphenol | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1980-01-01 | — | — | US | claimed |
| US-6696573-B1 | SYNTHESIS OF SUCH AS 2-(N-(2-(9H-CARBAZOL-2-YLOXY)ETHYL))-AMINO-1-((3 -METHYLSULFONYLAMINO)PHENYL)ETHANOL WITH ENHANCED OPTICAL PURITY | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2004-02-24 | — | — | US | disclosed |
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-12-04 | — | — | US | disclosed |
| CN-1377342-A | Process for preparation of tricyclic amino alcohol derivatives | ASAHI CHEMICAL IND (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1209150-A1 | PROCESSES FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-4618624-A | 3-amino-4-hydroxy(or alkoxy)phenethanolamine derivatives and pharmacologically-acceptable acid addition salts thereof for increasing the growth rate and/or improving the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0080595-B1 | ALKANESULFONANILIDE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF | AMERICAN CYANAMID COMPANY (US) | 1985-05-29 | — | — | EP | disclosed |
| US-4477680-A | 3-Amino-4-hydroxy(or alkoxy)phenethanolamine derivatives and _pharmacologically acceptable acid addition salts thereof for _increasing the growth rate and/or improving the lean meat to fat _ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
| EP-0080595-A1 | Alkanesulfonanilide derivatives and pharmaceutically acceptable acid addition salts thereof | AMERICAN CYANAMID COMPANY (US) | 1983-06-08 | — | — | EP | disclosed |
| US-4181681-A | 2-Amino-4-ethynylphenol | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1980-01-01 | — | — | US | disclosed |
| US-4181681-A | 2-Amino-4-ethynylphenol | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1980-01-01 | — | — | US | disclosed |
| US-4147858-A | Fluorocarbon ether bibenzoxazole oligomers containing reactive acetylenic terminal groups | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ADH1A, ADH1C, OXER1 | ALDH1A1 80/4885SMN1; SMN2 4201/4885LMNA 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.