Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4911299 | 0.95 | KDM4E (0.33) | TSHRSLC6A3SLC6A4SLC6A2KMT2A | |
| SCHEMBL6743192 | 0.78 | OPRM1 (0.39) | TSHRSLC6A3SLC6A4SLC6A2KMT2A | |
| SCHEMBL4818176 | 0.75 | MAPT (0.35) | TSHRKDM4EALDH1A1HSD17B10TMEM97 | |
| Formic Acid SCHEMBL4911312 | 0.72 | SMN1; SMN2 (0.35) | TSHRKMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6742634 | 0.71 | SLC6A4 (0.51) | TSHRSLC6A3SLC6A4SLC6A2KMT2A | |
| SCHEMBL9046812 | 0.71 | KDM4E (0.51) | TSHRKMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11224937 | 0.69 | DRD3 (0.43) | KDM4EDRD2DRD4DRD3 | |
| SCHEMBL10643008 | 0.69 | OPRL1 (0.47) | KMT2AKDM4ESIGMAR1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10652811 | 0.68 | POLB (0.49) | KMT2AKDM4ESIGMAR1DRD2DRD4 | |
| SCHEMBL12434732 | 0.64 | L3MBTL1 (0.56) | TSHRKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |